Browsing NUI Galway Theses (PhD Theses) by Title
Now showing items 100-119 of 1119
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Cache maintenance in federated query processing based on quality of service constraints
(2017-05-09)The Linked Open Data (LOD) Cloud forms a substantial and ever increasing portion of the global knowledge on theWorldWideWeb by contributing many distributed data sources. Due to the diversity of the knowledge that they ... -
Calendars, feasting, cosmology and identities: later Neolithic-early Bronze Age Ireland in European context
(2016-07-25)The aim of the study is to investigate the connections between calendar systems, large-scale feasting activities, changing representations of cosmological ideas and the formation of group identities from the Middle/Late ... -
Calibrated whole building energy simulation: An evidence-based methodology
(2011-01)Climate change, driven by global energy consumption, is one of the major challenges to humanity today. The buildings sector consumes a significant portion of global energy resources and much of this is due to inefficient ... -
Calibration of detailed building energy simulation models to measured data using uncertainty analysis
(2014-05-30)Over the past few decades, advances in technology, most notably the industrial revolution of the late 18th-century, has brought about dramatic improvements in the socioeconomic circumstances of developed nations. This has ... -
Calixarene-mediated protein assembly
(2014-05-23)Solved the first crystal structure of a protein-calixarene complex (at 1.4 Angstrom resolution). The results provide exact structural information on the amino acid preference of the anionic p-sulfonatocalix[4]arene (sclx4) ... -
The cannabinoid type-2 (CB2) receptor as a target for anti-inflammatory disease modification in Parkinson's disease
(2016-08-04)Parkinson’s disease is a multifaceted neurodegenerative disorder with no curative treatment. A key aspect in the pathogenesis of Parkinson’s disease is inflammation, which is initially triggered by dying neurons and which ... -
Caointeoireacht na Gaeilge: Béalaireacht agus Literathacht
(2012-09-19)Tá deighilt láidir idir scoláirí Gaeilge maidir leis an mbéalaireacht agus an litearthacht sa chaoineadh. Ar láimh amháin, maítear gur seánra béil é an caoineadh a bhfuil fianaise de ar fáil i lámhscríbhinní, agus ar an ... -
Carbohydrates as precursors to macrocyclic and iminosugar frameworks
(2017-09-30)Natural products have been perceived as privileged structures in drug discovery based on their evolutionary experience. Chapter 1, explores previous exploitation of this platform by medicinal chemists to identify some ... -
Cardiovascular disease and functional ability in older adults
(2015-06-03)Preservation of functional independence is important to older adults. The consequences of functional impairment (increased dependence on others for activities of daily living and requirement for nursing home care) place a ... -
A Carnivalesque Mirage: the Orient in Isabelle Eberhardt's Writings
(2012-12-10)As a woman who traversed the North African Orient in male costume, who spoke Arabic as well as French, who professed Islam while transgressing many of its instructions, Isabelle Eberhardt seems to fit within Mikhail Bakhtin¿s ... -
Cataloguing and linking publicly available biomedical SPARQL endpoints for federation - addressing aPosteriori data integration
(2017-05-12)During recent years the increasing adoption of Open Data Initiatives and Lined Data principles have lead to the creation of a globally distributed space of Linked Data that covers various domains such as Government, ... -
Cell Cycle-dependence of cisplatin-and carboplatin-induced dna damage
(2011-09-30)Platinum-based chemotherapeutic drugs such as cisplatin and carboplatin induce intra- and interstrand crosslinks, resulting in replication arrest, and cell death. Translesion synthesis by DNA polymerase eta, is one way in ... -
Cell sheet technology meets macromolecular crowding: The self-ssembly approach for corneal stromal development
(2015-05-01)Therapeutic strategies based on the principles of tissue engineering by self-assembly put forward the notion that functional regeneration can be achieved by utilising the inherent capacity of cells to create highly ... -
Cell wall immunocytochemistry and histology of hemiparasitism in Rhinanthus minor L. and Odontites vernus (Bellardi) Dumort: interactions at haustorial interfaces and implications for grassland biodiversity
(2013-11-21)Parasitic plants develop specialised grafting organs called haustoria to attach to and infiltrate host plant organs to access nutrients. The outcome of the parasitic process is largely determined where cell walls of the ... -
Cellular responses to endoplasmic reticulum stress: Role of autophagy and cell death
(2014-12-03)This PhD thesis describes cellular responses to the induction of endoplasmic reticulum (ER) stress, focusing on the role of autophagy and cell death. Pro-survival role of unfolded protein response (UPR) is analysed by ... -
Centriolar and ciliary responses to DNA damage
(2012-09-26)Centrosome duplication is tightly controlled and takes place only once every cell cycle. In recent years more light has been shed on the mechanism of centrosome duplication, with key players being identified and characterised. ... -
Centrosome cohesion: functions of C-NAP1
(2016-01-07)Double stranded DNA encodes the genetic material of the cell. Replication and segregation cycles are regulated in order to maintain the integrity of the DNA sequence from one cell cycle to the next. Detection of lesions ... -
Cerebral palsy in the West of Ireland and the application of the international criteria for the identification of acute intrapartum hypoxia: a cohort study.
(2012-05-09)Abstract Background Cerebral palsy is one of the most severe disabilities in childhood and occurs in 1-3 per 1,000 live births in Europe. This epidemiological study looked at a cohort of children with cerebral palsy to ... -
Chain transfer to solvent in the radical polymerization of acrylamide monomers, controlled/living radical polymerizations, including in supercritical carbon dioxide and preparation of carbon dioxide responsive micelles
(2014-12-11)Chapter 1 provides a general introduction to radical polymerization, including chain transfer, and controlled/living radical polymerization. A review of the literature since 2009 on heterogeneous controlled/living radical ... -
Characterisation of core histone sequences and nuclear mobility using a reproducible research approach
(2017-09-19)Chromatin is a dynamic complex that controls access to genetic information by undergoing structural reconfigurations. Understanding this dynamic can provide insights into the biological implications of chromatin ...