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Now showing items 51-60 of 1522
A molecular genetic investigation into stress sensing in the food-borne pathogen Listeria Monocytogenes: roles for RsbR and its paralogues
(2016-11-30)
The alternative sigma factor σB is conserved across several Gram-positive bacteria species as the major general stress response (GSR) regulator. For the food-borne pathogen Listeria monocytogenes, σB enables the bacterium ...
The assessment of communication skills during OSCEs: development and trialled implementation of a new standardised model using the MAAS-Global Instrument
(2016-01-19)
Communication skills (CS) are important skills that have a major impact in
healthcare outcomes. These outcomes include, for instance, increased patient
understanding, patient satisfaction and better pain control. With ...
Investigation of the role of nuclear factor kappa-B in mediating the effects of hypercapnic acidosis and mesenchymal stem cells in ventilation induced lung injury
(NUI Galway, 2016-11-08)
Introduction: ARDS is a syndrome of acute respiratory failure that presents with progressive arterial hypoxemia, dyspnea, and a marked increase in the work of breathing. Mechanical ventilation is necessary to support life ...
Molecular genetic investigation towards functions of imprinted genes in reproduction and seed development in Arabidopsis thaliana
(2017-01-26)
In flowering plants and placental mammals a subset of genes known as imprinted genes display full or partial suppression or activation to one of its alleles in a parent of origin dependent manner. During maternal and ...
Hybrid simulation of ethernet based intra-vehicle networks
(2016-12-09)
As Advanced Driver Assist Systems (ADAS) increase in complexity, it becomes essential to be able to rapidly prototype and test these systems in a reproducible and reliable way. This work explores the problem of simulating ...
“Teanga Náisiúnta na hÉireann?”: idé-eolaíocht agus polaitíocht i nGluaiseacht na Gaeilge 1893-1943
(2016-10-18)
Cuirim romham sa tráchtas seo iniúchadh a dhéanamh ar an dlúthbhaint idir gluaiseacht na Gaeilge agus na príomhpháirtithe polaitiúla Cumann na nGaedheal/Fine Gael agus Fianna Fáil chun an Ghaeilge a athbheochan mar ‘theanga ...
Narratives of slimming: women and weight management in Irish society
(2016-11-18)
This PhD study presents a feminist sociological analysis of the construction of narratives of slimming in Irish society. Theoretically, the study is informed by three main arguments: firstly, that the pursuit/attainment ...
Investigation of intron coevolution and the autoimmune potential of alternative splicing
(2016-07-20)
Introns are non-coding intergenic sequences that are routinely excised from nascent pre-mRNA transcripts by a process known as splicing. Although they do not contribute directly to the protein-coding sequences of genes, ...
The benign synthesis of bioactive heterocycles using photochemistry and hydrogen peroxide with hydrohalic acids
(2016-07-08)
Chapter 1 provides a pertinent review of recent photochemical homolytic aromatic substitution (HAS) literature. Photochemical methods for HAS include UV-light and visible light photoredox catalysis. Recently invented methods ...
The Effects of Electron-Withdrawing Ring Substituents on the Reactivity of Cyclopentadienyl Ruthenium Complexes
(2011-09-09)
This thesis describes the synthesis of ruthenium complexes which contain
cyclopentadienyl ligands with electron-withdrawing ring substituents and the effects of
these substituents on the reactivity of the metal centre. ...