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Now showing items 31-40 of 1119
An investigation of the immunometabolic interactions of obesity
(2013-09-04)
Human monocytes are classified as classical, intermediate and non-classical according to their surface expression of CD14 and CD16. They also represent precursors to atherogenic foam cells and macrophages in metabolically ...
Meseanchymal stem cell mediated sodium iodide symporter gene therapy of breast cancer
(2014-05-07)
Introduction: The Sodium Iodide Symporter (NIS) facilitates iodide accumulation in the thyroid and radioiodide imaging and treatment of thyroid disease. Studies have suggested that elevated levels of NIS expression in ...
Development of filtration technologies for effective, cost-efficient and robust water treatment
(2016-08-12)
The provision of high quality, potable water in a sustainable and effective manner is a
key challenge for water engineers, scientists, and policy makers. Urbanisation and
industrial development, along with population ...
A study of carbonation in stabilised peat
(2016-09-02)
In addition to the traditional drivers of cost and timely delivery, embodied energy (EE) and embodied carbon (EC) have emerged as major considerations in all aspects of large construction projects. This is due to stricter ...
In silico bone tissue engineering - a multiscale and multiphysics approach
(2016-07-26)
Mechanical stimulation in terms of fluid flow and mechanical strain can enhance the osteogenesis. Biomaterial scaffolds used in bone tissue engineering experiments have extremely complex geometry, which will result in the ...
A morpho-kinematic and spectroscopic study of bipolar planetary nebulae
(2015-09-28)
In this thesis, studies of the kinematic properties for a sample of Galactic bipolar planetary nebulae, based on optical and infrared observations, were performed us- ing a morpho–kinematic code, optical and NIR diagnostic ...
The genomic architecture of nucleolar organiser regions on the short arms of human acrocentric chromosomes
(2015-09-29)
Nucleolar Organiser Regions (NORs) are comprised of ribosomal gene (rDNA) arrays and adjacent sequences. Nucleoli, the sites of ribosome biogenesis and key regulators of cellular growth and proliferation, form around NORs. ...
Characterisation of novel Histone H3 RAD9 mutants defective in the DNA damage response in Saccharomyces cerevisiae
(2013-02-28)
The DNA damage response (DDR) is a signal transduction cascade, which regulates cell cycle progression, gene transcription and DNA repair. Histones also play a vital role in the activation of the DDR and have been shown ...
The health economics of obesity in Ireland
(2016-05-13)
An abundant literature exists linking obesity to a range of health conditions as well as premature mortality (Calle et al., 1999, Larsson et al., 1984, Jagielski et al., 2014, Kearns et al., 2014, Pi-Sunyer, 1999, Reilly ...
An exploration of the European landscape convention as a guiding framework for multi-scalar landscape governance in the territories of Catalonia (Spain) and the Republic of Ireland
(2016-05-13)
The spatial dimensions of many social, economic and environmental challenges
facing 21st century societies can be addressed through the idea of landscape. Scholars
working in the area of environmental and landscape change ...










