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Health literacy levels in women at risk of gestational diabetes mellitus attending antenatal services in University Hospital Galway
(2017-05-10)
Introduction
The 2011 population study on health literacy found that 40% of the Irish population had inadequate health literacy. There has been little research in Ireland and internationally on health literacy in pregnancy. ...
Evaluation of the efficacy of the Baska Mask
(NUI Galway, 2018-03-22)
The Baska mask is a new supraglottic airway device (SAD). Its novel features include a non-inflatable cuff consisting of a silicone membrane, and an oesophageal drainage system with sump reservoir, connected to 2 drainage ...
Investigating the mechanism of action and potential efficacy of Apolipoprotein E mimetics as therapeutic agents for the treatment of metastatic prostate cancer
(2017-10-04)
Prostate cancer is the most prevalent non cutaneous cancer diagnosed in Irish men and the third leading cause of death in males annually in Ireland. Therapeutic strategies currently consist of prostatectomy or radiation ...
Programmed DNA damage in myogenesis
(2017-02-23)
Skeletal muscle is a major tissue type in humans, comprising approximately 40% of total body mass in adults. Skeletal muscle is ultimately composed of elongated multinucleate cells known as myofibers. These myofibers are ...
Optimising the maturation rate of arteriovenous fistula (AVF) in patients with end stage renal disease (ESRD)
(2016-01-25)
A well-functioning Arteriovenous Fistula (AVF) has been shown to be the best modality for access in patients with end-stage kidney disease going for dialysis. Maturation of AVF is complex and depends on various biomechanical ...
The importance of a continuum of care before, during and after pregnancy in women with type 1 and type 2 diabetes along the Irish Atlantic seaboard
(2017-04-06)
Pregestational diabetes is the most common chronic medical condition to complicate pregnancy and is associated with an increased risk of morbidity and mortality for the mother-offspring pair. Optimising outcomes for this ...
Hypoxia activates the PTHrP – Zfp521 – MEF2C pathway to attenuate hypertrophy in mesenchymal stem cell derived cartilage
(2016-04-22)
The treatment of cartilage defects remains an unmet medical need as the current treatment options are currently sub-optimal as the most common treatment options; microfracture and autologous chondrocyte implantation (ACI) ...
Exosome-encapsulated microRNAs as circulating biomarkers for breast cancer
(2016-06-15)
Breast cancer is a heterogeneous group of diseases survival from which depends on stage at diagnosis. The development of blood-based biomarkers which may facilitate earlier detection and possibly subtype delineation remains ...
microRNA-mediated intercellular communication in the primary breast tumour microenvironment
(2014-08-30)
microRNAs (miRNA) have been highlighted as potential circulating biomarkers and as therapeutic targets for breast cancer. Recent evidence suggests that miRNAs are transported in protective microvesicles called exosomes, ...
Inflammatory-environment interactions as an approach to modelling Parkinson's disease
(2017-09-22)
It has been over 50 years since the first demonstration that levodopa was capable of reversing the motor dysfunction associated with Parkinson’s disease. In the intervening decades, although levodopa has remained the most ...