Now showing items 1-4 of 4
Novel mechanisms for neoadjuvant chemotherapeutic response monitoring in breast cancer
Breast cancer is the most frequently diagnosed female malignancy worldwide, causing the majority of cancer-related deaths amongst women. While the management of this disease has transformed dramatically in recent years, ...
Molecular mechanisms and tumour heterogeneity in breast cancer
MicroRNAs play a critical role in regulation of gene expression and are known to be dysregulated in breast cancer. The aim of this study was investigate four microRNAs miR-875-5p, miR-339-5p, miR-10a and miR-379 which were ...
The prognostic value of protein and microRNA biomarkers in breast cancer and their role in tumour progression
Identification of biomarkers has proven valuable in prognostication and treatment stratification of individual cases of breast cancer. microRNAs, short non-coding RNA molecules which negatively regulate translation of mRNA, ...
Role of MicroRNAs and unfolded protein response in breast cancer
Stressful conditions of the tumour microenvironment which overwhelm the folding capacity of the endoplasmic reticulum (EnR) activate an evolutionary conserved signalling pathway known as the unfolded protein response (UPR). ...