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microRNA-mediated intercellular communication in the primary breast tumour microenvironment
microRNAs (miRNA) have been highlighted as potential circulating biomarkers and as therapeutic targets for breast cancer. Recent evidence suggests that miRNAs are transported in protective microvesicles called exosomes, ...
Molecular mechanisms and tumour heterogeneity in breast cancer
MicroRNAs play a critical role in regulation of gene expression and are known to be dysregulated in breast cancer. The aim of this study was investigate four microRNAs miR-875-5p, miR-339-5p, miR-10a and miR-379 which were ...
The prognostic value of protein and microRNA biomarkers in breast cancer and their role in tumour progression
Identification of biomarkers has proven valuable in prognostication and treatment stratification of individual cases of breast cancer. microRNAs, short non-coding RNA molecules which negatively regulate translation of mRNA, ...