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Molecular investigation into the roles of Sigma B and the Stressosome in the response of Listeria monocytogenes to environmental stress
(NUI Galway, 2019-07-15)
The alternative sigma factor, SigB, has been studied extensively in Listeria monocytogenes, Bacillus subtilis and Staphylococcus aureus, and is known to regulate the general stress response in these bacteria. The activation ...
Novel multiplex isothermal nucleic acid amplification technologies for the detection of bacterial meningitis associated pathogens
(NUI Galway, 2019-02-28)
Infectious diseases, caused by pathogenic microorganisms such as bacteria, fungi or viruses, are a leading cause of significant global morbidity and mortality, with over 10 million associated deaths reported each year. ...
A study of the presentation and biological effects of biofilm component poly-N-acetylglucosamine from Staphylococcus aureus and Acinetobacter baumannii using novel multidisciplinary platforms and methods
(NUI Galway, 2019-09-24)
Biofilm formation on medical devices is major cause of concern in today’s society as implanted devices are associated with 60-70% of nosocomial infections. Poly-N-acetylglucosamine (PNAG) is a polysaccharide found on many ...