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Combustion kinetic studies of future transportation fuels and intermediates
(NUI Galway, 2020-10-22)
The transportation sector requires an abundant supply of fossil and/or bio-derived fuels,
which all produce significant quantities of greenhouse gas (GHG) emissions. The
transportation sector is expected to account for ...
An optical investigation into post compression aerodynamics in a dual opposed piston rapid compression machine
(NUI Galway, 2020-02-07)
Experimental chemical kineticists use rapid compression machines (RCMs) to verify models of global reactivity of fuels in as an ideal environment as possible, similar to those experienced in internal combustion engines. ...
Chemical diversity of some benthic cyanobacteria from French Polynesia and New Caledonia
(NUI Galway, 2020-08-04)
Cyanobacteria are often considered proliferative in relation with the global change affecting oceans worldwide and especially in the coral reefs of the Pacific Ocean. The bloom of the cyanobacteria in the Pacific Ocean are ...
Experimental studies of simple hydrocarbons in a shock tube
(NUI Galway, 2020-09-24)
Chemical kinetic models are needed to simulate fuel chemistry in combustion devices and to aid
in the development of new designs to reduce harmful emissions and maximize combustor performance.
However, these models need ...
Characterisation of bovine pericardium and alternative treatments for its application as biomaterial
(NUI Galway, 2020-04-09)
Bovine pericardium is an extensively used biomaterial utilised in a wide range
of biomedical devices such as bioprosthetic heart valves. The characterisation
techniques employed for the analysis of bovine pericardium and ...
Anisotropy Resolved Multidimensional Emission Spectroscopy (ARMES) for the analysis of Immunoglobulin G (IgG) type proteins
(NUI Galway, 2020-10-02)
Immunoglobulin G (IgG) is the main antibody used in the biopharmaceutical industry for therapeutic purposes. Monoclonal antibodies (mAb) are growing in the marked due to its high specificity and safety. Physical and ...
Study of protein-polymer nanoparticle interactions using advanced fluorescence-based approaches: Fluorescence fluctuation spectroscopy
(NUI Galway, 2020-09-30)
Biologics are a class of drug products that are produced in part or in its totality from living organisms, one of the main examples of which are therapeutic proteins. During the production, processing, and purification ...
The study of protein chemical modification using polarized Excitation Emission Matrix (pEEM)
(NUI Galway, 2020-11-30)
The advances in drug development and the increased use of biologics as therapeutics drives the need for more effective Process Analytical Technology (PAT) tools to measure biophysical changes during manufacturing and ...
Small-molecule-based crosslinking and bioconjugation of biomolecules
(NUI Galway, 2020-01-10)
Chapter 1: The chemical modification and bioconjugation of proteins is an expanding yet challenging area of chemical biology. The superior nucleophilicity of cysteine presents it as a uniquely reactive bioconjugation handle. ...
Toward dual-action platinum(IV) complexes with bioactive ligands as potent anticancer agents
(NUI Galway, 2020-02-20)
Platinum agents (cisplatin, carboplatin and oxaliplatin) have a crucial role in the treatment of many cancers for several decades. However, they have severe side effects and a high number of patients have intrinsic or ...