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On extending depth of field in fast photographic lenses
(NUI Galway, 2019-09-04)
Modern smartphone cameras are equipped with multiple camera modules. These modules are typically five millimetres in length limiting the focal length of the lens. To preserve resolution the entrance pupil of these lenses ...
Detection of faint exoplanets in multispectral data
(NUI Galway, 2019-04-15)
The detection of extrasolar planets is extremely difficult due to their extreme faintness and proximity to their parent stars. Direct, ground-based detection is particularly challenging and despite the incredible contrast ...
Metal-based dithiocarbamato glycoconjugates: a suitable strategy to target tumour glycolysis?
(NUI Galway, 2019-03-11)
Rapidly dividing tumour cells require higher amounts of nutrients and energy for their fast proliferation, and glucose is no exception (the so-called “Warburg effect”). Consequently, such increased demand of glucose by ...
Sources, concentrations, and screening of hazardous brominated flame retardants from waste streams in Ireland
(NUI Galway, 2019-04-12)
Brominated flame retardants (BFRs) are organohalogen compounds which are applied to polymer-based materials in order to meet fire safety standards. Some of the most commonly-used of these BFRs in consumer plastic over the ...
Supramolecular ‘Glues’ for protein recognition and assembly
(NUI Galway, 2019-12-06)
Supramolecules such as calixarenes, cucurbiturils and foldamers are rapidly emerging as tools for protein assembly. This thesis builds on past successes with some of these scaffolds. Previously, sulfonato-calix[4]arene was ...
Elucidating levels and pathways of human exposure in Ireland to POP-BFRs and PFOS (ELEVATE)
(NUI Galway, 2019-12-17)
BFRs such as hexabromocyclododecane (HBCDD) and polybrominated diphenyl ethers (PBDEs) were used as flame retardants (FRs) in soft furnishings, building insulation foams, electronic and electrical goods. Perfluoroalkyl ...
Towards improved performance of mediated glucose oxidising enzyme electrodes for biosensing and biopower applications
(NUI Galway, 2019-11)
Energy produced through enzymatic catalysis at electrodes, namely oxidation of glucose and
reduction of oxygen may be used to power devices. The goal of powering implantable or semiimplantable
medical devices through ...
Control of polymorphism, crystal size and habit in pharmaceuticals
(NUI Galway, 2019-09)
Crystallization is widely used as a purification method of Active Pharmaceutical Ingredients, APIs. During the process a crystalline compound is generally obtained, and it can display general properties and characteristics ...
Enhancing the bioavailability of active pharmaceutical ingredients through cocrystallization and coamorphization
(NUI Galway, 2019-12-19)
During drug research and development, improving the solubility of poorly water soluble drugs without chemically modifying the drug molecule is one of the biggest challenges for the pharmaceutical industry. Most medicines ...
Entry pattern matrices
(NUI Galway, 2019-03-29)
An entry pattern matrix (EPM for short) is a rectangular matrix in which each entry is an indeterminate. The same indeterminate may appear in multiple positions, but different indeterminates are independent. For a field ...