Now showing items 1-2 of 2
Triple negative breast cancer: outcomes, subtypes and implications for treatment
(NUI Galway, 2019-11-30)
Triple negative breast cancer (TNBC) is a heterogeneous subtype representing 15-20% of all breast cancers and is associated with a poor prognosis, despite the advances made in other breast cancer subtypes. TNBC is defined ...
Implications of histone H2AX abundance in breast cancer
(NUI Galway, 2019-12-09)
Histones are responsible for the packaging of DNA into a eukaryotic cell nucleus, and the H2A variant H2AX plays an important role in the DNA damage response (DDR). The phosphorylated form of H2AX, known as γH2AX, has been ...