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Now showing items 81-90 of 193
Marine and freshwater influences on the hydrography, oxygen dynamics and ecology of an anoxic lagoonal estuary, Lough Furnace, Mayo, Ireland
(NUI Galway, 2019-10-08)
Estuarine and coastal water bodies are amongst the most productive and diverse habitats, providing crucial ecological and economic benefits. However, owing to their position at the interface between continents and the ...
Implications of histone H2AX abundance in breast cancer
(NUI Galway, 2019-12-09)
Histones are responsible for the packaging of DNA into a eukaryotic cell nucleus, and the H2A variant H2AX plays an important role in the DNA damage response (DDR). The phosphorylated form of H2AX, known as γH2AX, has been ...
The Bangladesh National Blindness and Low Vision Survey - Identification of prevalence, causes and the need for eye care services
(NUI Galway, 2019-10-15)
Background:
Bangladesh is a densely populated, impoverished country in South Asia with inadequate health service provision for a variety of diseases including treatable ocular conditions. The aims of this comprehensive ...
The price of fear: Developing a behavioural assessment of fear-related avoidance incorporating dynamic response measures
(NUI Galway, 2019-09-30)
Introduction: Fears (e.g., of spiders, or heights) are maladaptive to the extent that they can cause us to avoid opportunities that could enrich our lives. Thus, avoidance is central to fear constructs. However, the roles ...
Split luciferase reporters of apoptosome formation: a bio-tool to identify new drug-like molecules
(NUI Galway, 2019-12-03)
Formation of apoptosome, a key multiprotein complex in mitochondrial-mediated apoptosis, is an essential step during normal development and deregulation of this event is associated with pathological conditions. The apoptosome ...
Mathematical models for the kinetics of some carbohydrate enzymes
(NUI Galway, 2019-10-17)
In this thesis, some mathematical models for the mechanism of action of carbohydrate enzymes are developed and analysed.
Chapter 1 provides a general introduction to enzymes and their applications. In Chapter 2, ...
Influencing factors in the implementation and management of routine enquiry for intimate partner violence (IPV) in antenatal care setting in Ireland: A case study
(NUI Galway, 2019-09-19)
Referred to any form of violence by either partner within an intimate relationship, intimate partner violence (IPV), is recognised as a serious global public health problem. IPV results in poorer health and quality of life ...
A constructivist grounded theory study of the enablers and development of trust in scrum teams
(NUI Galway, 2019-08-19)
The academic discourse is replete with aphorisms advocating the need for trust in Scrum teams. However, whilst trust is believed to be necessary to foster knowledge sharing and collaboration within the Scrum team no research ...
A study of the presentation and biological effects of biofilm component poly-N-acetylglucosamine from Staphylococcus aureus and Acinetobacter baumannii using novel multidisciplinary platforms and methods
(NUI Galway, 2019-09-24)
Biofilm formation on medical devices is major cause of concern in today’s society as implanted devices are associated with 60-70% of nosocomial infections. Poly-N-acetylglucosamine (PNAG) is a polysaccharide found on many ...
Towards improved treatment planning for head and neck microwave hyperthermia
(NUI Galway, 2019-10-08)
Hyperthermia is an emerging cancer treatment modality which involves applying heat to the malignant tumor. The heating can be delivered using electromagnetic energy, mostly in the radiofrequency or microwave range. Accurate ...