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Involving children and young people in social research: navigating the balance between protection and participation
(2016-10-14)
This thesis is an article-based PhD. Against the backdrop of the almost universal acceptance of the UN Convention on the Rights of the Child and the scholarly works comprising the ‘new social studies of childhood’, the ...
Investigation of the role of nuclear factor kappa-B in mediating the effects of hypercapnic acidosis and mesenchymal stem cells in ventilation induced lung injury
(NUI Galway, 2016-11-08)
Introduction: ARDS is a syndrome of acute respiratory failure that presents with progressive arterial hypoxemia, dyspnea, and a marked increase in the work of breathing. Mechanical ventilation is necessary to support life ...
Hybrid simulation of ethernet based intra-vehicle networks
(2016-12-09)
As Advanced Driver Assist Systems (ADAS) increase in complexity, it becomes essential to be able to rapidly prototype and test these systems in a reproducible and reliable way. This work explores the problem of simulating ...
Modelling shear-induced platelet aggregation in general flow
(2016-11-07)
Blood-contacting biomedical devices are ubiquitous in current medical practice. Blood is very sensitive to non-physiological conditions, and it can be harmed by the biomedical device in a number of different ways. A very ...
Adaptive responses of campylobacter jejuni to antibiotic and biocide selection pressures in chemostat culture
(2016-04-18)
Campylobacter jejuni (C. jejuni) is a zoonotic pathogen of major public health importance and is the leading cause of gastroenteritis woldwide. Poultry is regarded as one of the most important reservoirs for Campylobacter ...
The ontology of technology: a Heideggerian perspective
(2016-06-30)
The question concerning technology lies at the heart of human existence. As such it must take a central place in philosophy today. This importance, however, is veiled by a historical interpretation of technology as ...
Media and disability - issues of portrayal and access
(2016-04-29)
This thesis begins with the premise that freedom of expression is the cornerstone of a democracy and any limitation on it must be prescribed by law, be in support of a legitimate aim and be necessary in a democratic society. ...
A study of factors influencing anomerisation reactions
(2016-07-18)
This thesis involves an investigation into the anomerisation reaction and strategies by which the reaction can potentially be improved and provide a greater understanding of factors influencing the reaction. There has been ...
Pro-survival pathways in triple negative breast cancer: Focus on the roles of RIP2 and HSPB1
(2016-10-10)
Triple negative breast cancers (TNBC) lack estrogen and progesterone receptors, and HER-2 markers rendering them resistant to current targeted therapies. Most TNBCs show basal-like characteristics and the terms TNBC and ...
Unemployment inflows and outflows in the UK: a micro economometric analysis
(2016-06-09)
The unemployment rate is a function of both the inflows to unemployment and the outflows from unemployment. Understanding the unemployment rate requires an understanding of the flows that drive the rate. This thesis ...