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Applied learning. A design model for further education in the 21st century
(2015-11-23)
Undertaken over four years, this research was both an investigation of the adoption of an applied learning approach for further education (FE) course delivery in the 21st century, and the development of an educational model ...
The kinesin KIF18B interacts with 53BP1 and is required for efficient double strand break repair
(2015-11-19)
Genetic changes can lead to detrimental genomic instability, mutagenesis, oncogenesis and premature aging. The DNA damage response (DDR) is responsible for safeguarding the genome from such harmful alterations.
53BP1 ...
Assessing and training early emergent derived relational responding in children with autism
(2015-09-30)
Many children with autism fail to develop generative language despite intensive teaching; their language can be described as “rote”. Research in the area of derived stimulus relations, in particular Relational Frame Theory ...
Genetic determinants of disease characteristics of inflammatory bowel disease and diverticulitis
(2015-05-05)
Background: Inflammatory Bowel Disease (IBD) is a complex, multigenic disease in which both the innate and adaptive immune systems play a strong role. Although over 40 microbes including bacteria, viruses and yeasts and ...
Human induced pluripotent stem cells as a model for neurodevelopmental disease
(2015-10-01)
Abstract
Autism spectrum disorders (ASD) are neurodevelopmental disorders which encompass a wide range of symptoms, including intellectual disability and delayed development, while the phenotype can range from mild to ...
Utilization of social breadcrumbs for user profiling in personalization
(2015-10-12)
Personalization efforts aim to alleviate the ``information overload" problem in an attempt to help users address their information needs in the best way possible. An increasing number of systems that employ personalization ...
The right to a healthy environment: a rights based approach to environmental issues
(2015-12-15)
This thesis analyses the Right to a Healthy Environment (RHE) and identifies the added value of rights-based approaches (RBAs) in the broader context of sustainable development. It focuses particularly on the requirement ...
Star formation in extreme environments
(2015-12-22)
The study of star formation bridges many vastly disparate scales. From the small, nearby, quiescent cores of low mass star formation, to the highly turbulent conditions in which the most massive stars form, to the extreme ...
Impacts of DNA damage on the pericentriolar material and centriole duplication
(2015-12-03)
The centrosome consists of two barrel-shaped centrioles embedded in a proteinaceous pericentriolar material (PCM), a highly organised scaffold that serves as a platform for proteins that regulate spindle assembly, protein ...
Using mixed methods to develop and test a theory of clinic attendance behaviour among young adults with type 1 diabetes
(2015-09-24)
Background Clinic non-attendance among young adults with type 1 diabetes has been widely reported in previous research. Research suggests that regular attendance at diabetes clinics may be particularly important for young ...