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Cellular interactions in the tumour microenvironment during inflammation-associated carcinogenesis
(2017-11-30)
The colon tumour microenvironment is highly stromal in composition and a greater stromal cell density correlates with a poor prognosis for patients. The majority of these stromal cells are of mesenchymal origin (MSCs) and ...
Preserving control: understanding people's experiences before, during and after involuntary admission under the Mental Health Act 2001
(2016-06-08)
Aim: To generate a grounded theory to understand people’s experiences before, during and after involuntary admission and/or detention.
Background: The MHA (2001) provides a legal framework for the involuntary admission ...
Acting is believing: ritual, memory, and performance in the plays of Enda Walsh
(2016-10-17)
In this research, I examine the relationship between ritual, memory, and performance and contemporary theatrical creation methods, specifically with reference to the works of Enda Walsh. I use Walsh's plays as a case study ...
Glycosylation and glycoengineering of recombinant antibody fragments in Escherichia coli
(2016-11-14)
Recombinant protein production (RPP) in Escherichia coli benefits from a long history of research which has facilitated the development of a plethora of strains and vectors suited to RPP applications. The identification ...
Development and evaluation of platform-based SERS substrates for detecting cancer biomarkers at ultra-low concentrations
(2017-04-27)
Surface Enhanced Raman Scattering (SERS) has proved to be a powerful spectroscopic tool since its discovery in 1973. Advances in nanofabrication techniques increasingly allow for the manufacture of complex nanostructured ...
Pathogen genomics of methicillin resistant staphylococcus aureus and leishmania
(2017-02-15)
Infectious diseases caused by the single-celled eukaryotic parasite Leishmania and the methicillin-resistant Staphylococcus aureus (MRSA) bacterium are major public health problems in many countries. In this thesis, I use ...
Integrating Heterogeneous Data by Extending Semantic Web Standards
(2012-09-28)
In enterprises different software applications are used to manage specific functions: customer relations, human resources, and manufacturing, each requiring specialised software. Relational databases are commonly used as ...
Litearthacht aosach sa nGaeltacht: staidéar ar riachtanais agus ar chumas aosach maidir le litearthacht i nGaeilge
(2015-08-30)
Ba í aidhm an staidéar taighde seo ná tuiscint a fháil ar dhearcadh, chumas agus riachtanais lucht labhartha na Gaeilge sa nGaeltacht maidir le litearthacht sa teanga sin i gcúinsí an tsíorbhrú atá ar an nGaeilge mar theanga ...
Graph summarisation of web data: data-driven generation of structured representations
(2016-08-31)
The advent of the Internet enabled the sharing of information between people all around the world. Projects like Wikipedia have made human knowledge accessible to anybody with a simple mouse click. The Linked Data movement ...
Between realities: investigating temporal relations between stillness and movement in contemporary artists' lens-based imagery
(2017-02-23)
Temporal registers of stillness and movement in lens-based imagery, traditionally defined under the terms of photography and film, are in many ways two faces of the same coin, one representing time as a frozen moment and ...