Search
Now showing items 21-30 of 170
Factors that facilitate regulatory approval for drug/device combination products in the European Union and United States of America: a mixed method study of industry views
(2015-09-30)
Drug/device combination products play a vital role in diagnosis and treatment of a wide range of disorders, including chronic disorders such as heart disease, cancer, respiratory disease, and diabetes. Doctors consider ...
Investigation of IRE1/XBP1s pathway and its potential as a therapeutic target in breast cancer
(2015-09-18)
X-Box binding protein 1 (XBP1) is an integral component of the unfolded protein response
(UPR), a pro-survival mechanism, triggered by the onset of endoplasmic reticulum stress.
Activation of the endoplasmic reticulum ...
The impact of preterm birth on adaptive behaviour and participation in childhood occupation
(2015-10-02)
Background: Premature infants are at increased risk of developing motor,
cognitive and behavioural impairments compared with infants born at term.
Outcome studies have tended to focus their assessments predominately ...
The Irish Folklore Commission Questionnaire System, 1936-1945
(2015-12-02)
This project examines the importance of the forty-nine questionnaires issued between 1935 and 1945 by the Irish Folklore Commission. The Irish questionnaire system was modelled on the use of the collecting tool in Scandinavian ...
Dream islands within the fabric of poetic consciousness – reverie, dream and dreamlikeness in Robert Walser’s Berlin novels 'Geschwister Tanner' and 'Jakob von Gunten'
(2015-10-27)
This dissertation reconstructs firstly the dreamlikeness which determines Walser’s two Berlin novels Geschwister Tanner and Jakob von Gunten, and secondly a poetology of the denoted dream texts (representations of dreams) ...
Subversive narrative and Mexicanidad in the works of Luis Buñuel and Juan Rulfo
(2015-09-30)
This thesis is a comparative study of the Mexican works of Luis Buñuel and Juan Rulfo, focussing on the period from 1950 to 1962. It examines the impact of Mexican cultural nationalism on the artistic practices of a writer, ...
A conceptual history of the idea of self-causation: from Plato's forms to Hegel's concrete universal
(2015-09-29)
The dissertation is a historical-cum-conceptual examination of the idea of self-causation (causa sui). In the Western metaphysical tradition, self-causation has been understood in two ways: (i.) as an individual existent’s ...
Contribution of non-histone proteins to chromatin structure and stability
(2015-10-30)
Histones are responsible for packaging the genomes of almost all eukaryotes into fundamental repeating nucleosome units. The packaging must facilitate compaction into the cell nucleus but also enable dynamic access to the ...
Investigations into assimilating high-frequency radar data into a three-dimensional hydrodynamic model of a wind-dominated coastal water body
(2015-10)
Accurate forecasting of surface currents in coastal waters is of great importance for operations such as search and rescue operations and marine energy extraction. Numerical models and measurements are two powerful ...
Topics in cocyclic development of pairwise combinatorial designs
(2015-10-14)
This thesis is a compilation of results dealing with cocyclic development of pairwise combinatorial designs. Motivated by a classification of the indexing and extension groups of the Paley Hadamard matrices due to de ...