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Representations of genders and ethnicities in the historical fiction of Mercedes Valdivieso and Gustavo Frías
(2016-08-26)
This thesis analyses the ways in which Chilean authors Mercedes Valdivieso and Gustavo Frías re-examine and engage with ideas of gender and ethnicity through their fictional representation of Catalina de los Ríos y Lisperguer ...
Sparse grid methods for singularly perturbed problems
(2016-05-09)
This thesis is concerned with the design, analysis and implementation of sparse grid finite element methods applied to singularly perturbed partial differential equations, in two and three dimensions.
Typically, sparse ...
In vitro, pre-clinical and commercial evaluation of a novel xeno- and serum-free culture system for production of human bone marrow derived mesenchymal stem cells for bone regeneration
(2016-10-21)
The therapeutic potential of mesenchymal stem cells (MSCs) is recognised in treating a wide range of debilitating diseases. For clinical-scale manufacturing, serum-free and xenogenic-free media formulations have been ...
Screamingly funny: A critical approach to the comedic anti-war novels of Joseph Heller, Kurt Vonnegut, Tom Robbins and Tony Vigorito
(2016-10-14)
This thesis investigates the use of humour in American anti-war novels in the second half of the twentieth century, through an analysis of joke-work in Joseph Heller’s Catch-22 (1961), Kurt Vonnegut’s Slaughterhouse-Five ...
Exploring the role of glycosylation in vascular biology, immunology,and stem cell biology
(2016-09-30)
Carbohydrates are important modulators in various biological and physiological
processes. They are present ubiquitously and coat all cells, forming the glycocalyx of the cell. Glycosylation, a type of post-translational ...
Entrepreneurial networking and the development of marketing capabilities in SMEs. A study of Irish entrepreneurs
(2016-09-16)
It is widely accepted across the marketing, entrepreneurship and strategic management literatures that relationships and networks are instrumental for the growth and performance of SMEs. In particular, in the entrepreneurial ...
Immunogenicity of allogeneic mesenchymal stem cells
(2016-10-20)
Allogeneic mesenchymal stem cells (allo-MSC) are a promising “off-the-shelf” therapy and are often cited as failing to elicit anti-donor immune responses. Intra-muscular (IM) administration may be the optimal route for ...
Neuroanatomical dysconnectivity in bipolar disorder
(2016-10-13)
Bipolar Disorder (BD) is a major psychotic illness characterized by cyclic mood dysregulation. The dysconnectivity hypothesis suggests that psychotic illnesses arise not from regionally specific focal pathophysiology, but ...
Human endogenous retrovirus K (HERV-K) in prostate cancer
(2016-08-08)
Millions of years of infection by viral agents have left their mark on the human genome in the form of human endogenous retroviruses (HERVs). These retroelements integrated into our germline, became subject to Mendelian ...
James Larkin and the British, American and Irish Free State Intelligence Services: 1914-1924
(2016-02)
This thesis takes the form of a case study and is an investigation of the activities of James Larkin between October 1914 and June 1924. It is an analysis of how capitalist states dealt with Larkin in the context of his ...