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Now showing items 161-170 of 170
Endocannabinoid regulation of neuroinflammatory responses following acute systemic viral (TLR3) and bacterial (TLR4) infection
(2015-10-14)
Toll like receptors (TLRs) are key players in host defence, homeostasis and response to injury. However, uncontrolled and aberrant TLR activation has been proposed to trigger the onset of certain neurodegenerative disorders ...
Digital ensemble: exploring the design of technology-enhanced learning to mobilise and augment students' engagement with English literature
(2015-06-24)
Students are disengaging from learning and literature learning in post primary education in Ireland due to an over-emphasis on rote learning practices and the constraints of high stakes, summative assessments (Chief ...
Subversive narrative and Mexicanidad in the works of Luis Buñuel and Juan Rulfo
(2015-09-30)
This thesis is a comparative study of the Mexican works of Luis Buñuel and Juan Rulfo, focussing on the period from 1950 to 1962. It examines the impact of Mexican cultural nationalism on the artistic practices of a writer, ...
The right to a healthy environment: a rights based approach to environmental issues
(2015-12-15)
This thesis analyses the Right to a Healthy Environment (RHE) and identifies the added value of rights-based approaches (RBAs) in the broader context of sustainable development. It focuses particularly on the requirement ...
Golden cages: refugees, camps and the politics of law
(2015-12-09)
This thesis explores the interplay between the refugee as a figure and the refugee camp as a space, and interrogates how this interplay has informed international refugee law as well as examining the gaps in international ...
Irish immigrants in the Rural U.S. Slave South
(2015-09-16)
This dissertation investigates the Irish immigrant experience in the rural areas of the U.S. slave South before the American Civil War. Specifically, it focuses on the analysis of the Irish immigrants' involvement with ...
The Irish Folklore Commission Questionnaire System, 1936-1945
(2015-12-02)
This project examines the importance of the forty-nine questionnaires issued between 1935 and 1945 by the Irish Folklore Commission. The Irish questionnaire system was modelled on the use of the collecting tool in Scandinavian ...
Investigation of IRE1/XBP1s pathway and its potential as a therapeutic target in breast cancer
(2015-09-18)
X-Box binding protein 1 (XBP1) is an integral component of the unfolded protein response
(UPR), a pro-survival mechanism, triggered by the onset of endoplasmic reticulum stress.
Activation of the endoplasmic reticulum ...
Factors that facilitate regulatory approval for drug/device combination products in the European Union and United States of America: a mixed method study of industry views
(2015-09-30)
Drug/device combination products play a vital role in diagnosis and treatment of a wide range of disorders, including chronic disorders such as heart disease, cancer, respiratory disease, and diabetes. Doctors consider ...
Narrating in/security: women's activism in Kashmir
(2015-09)
This thesis explores women activists’ narratives of everyday experiences of in/security through a qualitative case study in Kashmir, northern India. In order to gather women’s in/security narratives I conducted 13 in-depth ...