Search
Now showing items 1681-1690 of 1703
Thrombus analogue material: Mechanical characterisation and use in in-vitro modelling of acute ischemic stroke treatment
(NUI Galway, 2020-06-03)
Acute ischemic stroke (AIS), which accounts for approximately 85% of all strokes globally, is among the leading causes of death and long-term disability. It occurs when a blood clot causes an occlusion in a blood vessel, ...
Investigation of fluid dynamics in a vibrating mesh nebulizer using the finite volume particle method
(NUI Galway, 2020-12-17)
In Aerogen aerosol drug delivery technology, an aperture plate vibrates at high frequency under a piezoelectric drive. Liquid drug stored on one side of the plate passes through the apertures to form an aerosol of microscopic ...
Diagnostic insights from twenty years of bilateral inferior petrosal sinus sampling for Cushings Disease at Mayo Clinic (1998-2018)
(NUI Galway, 2020-03-02)
Pituitary-dependent Cushing syndrome (CS), referred to herein as Cushing Disease (CD), is the most common cause of endogenous CS. The challenge for diagnosing CD includes difficulty identifying the often small pituitary ...
The genesis of the Europeanisation of the Northern Ireland peace process
(2018-01-17)
The thesis examines the economic and political contributions of the European Union
(EU) to the Northern Ireland peace process, tracing the genesis of EU involvement and
analysing how it acted as an arena in which to ...
Immunomodulation in mesenchymal stem cell therapy for osteoarthritis: mechanistic insights on the role of cell death and engraftment
(NUI Galway, 2018-11-02)
Osteoarthritis (OA) is a degenerative pathology of the articular cartilage causing chronic
pain and disability in millions of individuals. In OA synovia, resident macrophages and
infiltrated lymphocytes contribute to the ...
Experimental characterisation, computational modelling and design tool development for fretting fatigue and wear in flexible marine risers
(2017-09-25)
Fretting is a key concern in the fatigue design of the pressure armour layer of flexible marine risers, due to the combination of extreme global dynamic loading conditions and the local geometrical-tribological conditions ...
A biological and pharmacological investigation of the unfolded protein response in models of breast cancer
(NUI Galway, 2020-11-20)
Breast cancer is the most common malignancy in women worldwide. At the molecular level, breast cancer is a heterogeneous disease. For example, the claudin low subtype of breast cancer is characterised by epithelial-mesenchymal ...
Environmental assessment of freshwater aquaculture in Ireland
(NUI Galway, 2020-12-11)
Aquaculture is the fastest growing food production activity in the world and has been for the last several decades. With over 60% of wild fish stocks at or below their maximum sustainable yield, it is expected that to ...
Porcine peritoneum: A multifunctional xenograft for a diverse range of clinical indications
(NUI Galway, 2020-12-18)
Decellularised xenografts are an inherent component of regenerative medicine. Their preserved structure, mechanical integrity and biofunctional composition have well established them in reparative medicine for a diverse ...
Characterisation of bovine pericardium and alternative treatments for its application as biomaterial
(NUI Galway, 2020-04-09)
Bovine pericardium is an extensively used biomaterial utilised in a wide range
of biomedical devices such as bioprosthetic heart valves. The characterisation
techniques employed for the analysis of bovine pericardium and ...