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Now showing items 1641-1650 of 1724
Writing through the trauma of her past: Patterns of repression and a fragmented sense of self in the literature of Christa Wolf
(2017-09-08)
This project aims to offer a re-evaluation of the literature of Christa Wolf and change the focus of the questions posed in relation to her literary legacy. Shifting the focus away from a denouncement of her character and ...
Suspended pratfalls: Slapstick in contemporary art
(2018-02-22)
This thesis considers a comedic trend in contemporary art that engages in a process of critical enquiry towards its own material structure and contextual frameworks. Certain contemporary artists employ a form of critical ...
Bayesian imputation of right censored data in time-to-event studies
(NUI Galway, 2018-03-20)
In time-to-event studies subjects are followed until the event of interest has happened.
Subjects who do not experience the event are referred to as censored. Due
to censoring, methods of plotting individual survival ...
Fibrin-in-fibrin intervention for enhanced dopaminergic graft survival in Parkinson’s disease: Special focus on brain N-glycans
(NUI Galway, 2019-11-07)
Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disorder caused due to the selective loss of dopaminergic neurons in substantia nigra pars compacta (SN) translating into the classical motor symptoms ...
The dark side of humanity: psychopathy, psychiatry and human nature
(2017-10-11)
Psychopathy or antisocial personality disorder is generally conceived as a neurophysiological disorder undermining moral reasoning or sentiment, leading to behaviour which contravenes social and moral norms. This psychiatric ...
Endocannabinoid modulation of TLR3-induced neuroinflammation
(2017-10-06)
Toll-like receptors (TLRs) play a key role in the recognition and activation of the innate immune system in response to infection. However, aberrant TLR activation has been implicated in predisposing to, and exacerbating, ...
Characterisation of the cellular responses to CDC7 inhibition in breast-derived human cells
(2017-10-06)
CDC7 plays a role in DNA replication initiation and cell cycle regulation. Inhibition of CDC7 kinase by siRNA triggers a p53-independent apoptotic cell death in cancer cells but not in human fibroblast suggesting this ...
Unsupervised target-driven artificial neural networks for dynamic DDoS mitigation within the ISP domain
(NUI Galway, 2020-10-08)
Contemporary Distributed Denial-of-Service (DDoS) attack vectors can change their
traffic patterns during the time when an attack is underway, and as such, pre-trained
models can struggle to identify new attack traffic ...
From hybrid bodies to haunted bodies: Mobile technologies, affect and theatre
(2017-09-22)
Mobile digital technologies - from smartphones, to wearables, to pervasive technologies - are transforming the ways in which we experience our own bodies, and the ways in which we experience the world through our bodies. ...
A modified depth function for outlier detection in multivariate data with applications
(NUI Galway, 2020-09-24)
Data Science is the new and exciting interdisciplinary response that has emerged as a consequence of the staggering amounts of data generated in many new forms from digital images to audio to text. It is an interdisciplinary ...