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A Social Marketing Partnership Framework: An Extension of Morgan and Hunt’s (1994) Commitment - Trust Key Mediating Variable Model
(2012-09-19)
The type of transformational change needed to address the complex and wicked issues that permeate today's society cannot be facilitated without the adoption of multi-sectoral social marketing partnerships. This research, ...
Criminal children in post-Famine Connacht: Poverty, crime and punishment, with a particular focus on the period 1854-1870
(2012-09-21)
This study examines the extent and nature of juvenile crime in Connacht from 1854 to 1884, and looks at how poor and criminal children were treated in the west of Ireland in this period. Most studies of juvenile crime in ...
Identification of prognostic targets in breast cancer using immunohistochemical and in situ hybridisation methodologies
(2011-12-16)
Advances in our understanding of the molecular mechanisms underlying breast cancer are leading to improvements in its management. Many of the recent gene-based signatures developed for breast cancer have highlighted the ...
Predicting the long-term performance of low-cost phosphorus-sorbing materials using small-scale adsorption column experiments
(2017-07-31)
Anthropogenic phosphorus (P) and nitrogen (N) inputs to aquatic environments have rapidly increased in magnitude since the middle of the twentieth century, and nutrient pollution has become the primary threat to global ...
Multi-Dimensional Fluorescence Spectroscopy for Quantitative Cell Culture Media Analysis
(2012-10-17)
Industrial mammalian cell culture uses complex media, such as eRDF, to support cell growth and product formation as an integral part of the process; as a result the analysis of media variance/quality is of critical ...
Analysis of Saccharomyces cerevisiae Mec1 and Rad9 functions in the DNA Damage Response
(2012-10-01)
The maintenance of genome integrity is critical for cell proliferation and survival of
all organisms. Central to the DNA Damage Response are signal-transduction
pathways, termed DNA damage checkpoints, conserved from ...
Decoy Receptors block tumour cell eradication by TRAIL - Molecular engineering of TRAIL to evade decoy receptors
(2012-06-29)
Tumour necrosis factor-related apoptosis inducing ligand (TRAIL) is a cytokine expressed by immune cells which selectively eradicates a wide range of cancer cells while leaving normal healthy cells unharmed. TRAIL binds ...
Protein-carbohydrate interactions and structural characterization of Ralstonia solanacearum lectin
(2017-03-20)
Ralstonia solanacearum is a bacterium which causes fatal damage to hundreds of agricultural plants such as potato or tobacco. It produces two lectins that are involved in attachment of the bacterium to the host. One of ...
From Connemara to Minnesota: The Nugent Emigration Scheme, 1880
(2016-05-10)
Abstract
This study examines an assisted emigration scheme undertaken by Father James Nugent of Liverpool in June 1880. With the support of Bishop John Ireland of St Paul, Minnesota, Nugent transferred thirty-five destitute ...
A systems engineering approach to equipment qualification in healthcare
(2015-08)
Equipment Qualification is a formal quality assurance process in manufacturing which establishes confidence that specified equipment is ‘ready for its intended use’. This thesis, in drawing parallels between requirements ...