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Role of Rad9 cell cycle phosphorylation in the regulation of Chk1 activation
(2012-01-07)
DNA damage checkpoints are triggered in response to DNA insults. Once activated,
these pathways prevent replication and segregation of the damaged DNA. In addition
to cell cycle delays they regulate repair, transcription ...
Analysis of the DNA damage response in model systems
(2014-07-24)
The integrity of our DNA is constantly threatened by endogenous and exogenous sources of damage. In the absence of sufficient repair mechanisms, this damage can lead to mutations, potentially resulting in the development ...