Now showing items 1-3 of 3
Therapeutic targets for duchenne muscular dystrophy
(NUI Galway, 2019-07-05)
Duchenne Muscular Dystrophy (DMD) is a progressive X-linked fatal muscle degenerative disorder caused by the absence of the sarcolemmal associated dystrophin-glycoprotein complex (DGC) that connects the intracellular ...
Mechanistic insights into novel cellular therapy strategies for the treatment of corneal allograft rejection
(NUI Galway, 2019-02-14)
It has previously been demonstrated by our lab that tolerogenic dendritic cells (tDCs) prolong corneal allograft survival. This study revealed that tDCs had significantly higher levels of sialic acid on the cell surface ...
Evaluation of human induced pluripotent stem cell-based cellular models for pathological investigation of genetic skeletal diseases
(NUI Galway, 2019-02-15)
The uniqueness of stem cells endows them with the capacity to be used as a valuable tool in the field of pathology, particularly the one from patients. Patient-specific cellular model can be generated by deriving donor-specific ...