The Baska mask is a new supraglottic airway device (SAD). Its novel features include a non-inflatable cuff consisting of a silicone membrane, and an oesophageal drainage system with sump reservoir, connected to 2 drainage ...

Purpose: To develop a subchondral defect in a rabbit model and assess cartilage repair using a mesenchymal stem cell-seeded scaffold. Materials and Methods: To achieve this goal, a bovine explant model and two pilot ...

It has, for many years, been acknowledged that “breast cancer” is an umbrella term for many genetically and immunophenotypically distinct malignancies of the breast. Treatment paradigms are shifting in direct response to ...

Zebrafish are a versatile experimental model which have progressed the fields of many research areas through both genetic and pharmacological studies. In this thesis I studied a novel zygotic gene, nanor, in zebrafish and ...

The amount of biomedical data produced by DNA-sequencing, by curated knowledge on disease mechanisms and treatments, by results from biochemical and pharmaceutical research and by many other data generation studies is ...

There are several detrimental events that occur in the aftermath of a spinal cord injury (SCI); these include glial scar formation, accumulation of axon growth inhibitors and immune mediators. These events present challenges ...

The endoplasmic reticulum (EnR) stress is a common phenomenon in various cancers such as breast, colorectal, skin and hepatocellular carcinoma. Several pathophysiological events (e.g., radiation, aneuploidy, oncogenic ...

Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is a congenital heart disorder characterized by replacement of the ventricular myocardium with fibrofatty tissue. The majority of cases are due to mutations in genes ...

Background: Out-of-hospital cardiac arrest (OHCA) is the most critical health event that occurs in the community. When the heart stops pumping blood, if resuscitation is not started, biological death will occur within ...

Autism spectrum disorder (ASD), a multi-factorial disease, often has co-morbidity with epilepsy, which is associated with excessive neuronal firing. The pre-synaptic protein Neurexin1 (NRXN1) signals bi-directionally through ...