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microRNA-mediated intercellular communication in the primary breast tumour microenvironment
(2014-08-30)
microRNAs (miRNA) have been highlighted as potential circulating biomarkers and as therapeutic targets for breast cancer. Recent evidence suggests that miRNAs are transported in protective microvesicles called exosomes, ...
Diet and renal outcomes
(2014-11)
Chronic Kidney Disease (defined by decreased glomerular filtration rate and proteinuria) is associated with significant morbidity, increased cardiovascular risk and premature mortality. Advanced chronic kidney disease, ...
The prognostic value of protein and microRNA biomarkers in breast cancer and their role in tumour progression
(2014-05-14)
Identification of biomarkers has proven valuable in prognostication and treatment stratification of individual cases of breast cancer. microRNAs, short non-coding RNA molecules which negatively regulate translation of mRNA, ...
Endocannabinoid modulation of TLR4-induced neuroinflammation: implications for autism spectrum disorders
(2014-07-07)
Neuroinflammation is a key component of various neurological diseases including Alzheimer's disease, Parkinson's disease, multiple sclerosis and psychiatric and neurodevelopmental disorders such as depression and autism. ...
Molecular mechanisms and tumour heterogeneity in breast cancer
(2014-05-07)
MicroRNAs play a critical role in regulation of gene expression and are known to be dysregulated in breast cancer. The aim of this study was investigate four microRNAs miR-875-5p, miR-339-5p, miR-10a and miR-379 which were ...





