Now showing items 1-5 of 5
Therapeutic targets for duchenne muscular dystrophy
(NUI Galway, 2019-07-05)
Duchenne Muscular Dystrophy (DMD) is a progressive X-linked fatal muscle degenerative disorder caused by the absence of the sarcolemmal associated dystrophin-glycoprotein complex (DGC) that connects the intracellular ...
Investigations of spicules and spicule formation in Haplosclerida (Porifera, Demospongiae) using a multidisciplinary approach
(NUI Galway, 2019-01-09)
Sponges are simple animals and their body is formed by different cell types and a dense skeleton either of collagen, chitin or spicules made of amorphous silica or calcium carbonate that they secrete. The phylum Porifera ...
Characterisation of human nucleolar organisers located in previously uncharted regions of the human genome
(NUI Galway, 2019-01-18)
The nucleolus is a large, sub-nuclear domain and the site of ribosome biogenesis. Nucleoli form around chromosomal loci called ‘nucleolar organiser regions (NORs) located on the short arms of the human acrocentric ...
Computational modelling of the coupled electro-mechanical behaviour of neurons
(NUI Galway, 2019-01-22)
Recent experimental evidence has uncovered complex biophysical phenomena accompanying the electrical activity of nervous cells. Now emerging theories refer to the electric pulse, i.e. the Action Potential (AP), as an ...
Image super-resolution for consumer thermal cameras
(NUI Galway, 2019-01-21)
This thesis attempts to solve a problem currently faced by consumer-grade thermal cameras. Consumers have grown accustomed to the high pixel counts and high resolution offered by the modern smartphone, while the performance ...