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Genetic determinants of disease characteristics of inflammatory bowel disease and diverticulitis
(2015-05-05)
Background: Inflammatory Bowel Disease (IBD) is a complex, multigenic disease in which both the innate and adaptive immune systems play a strong role. Although over 40 microbes including bacteria, viruses and yeasts and ...
Analysis and interpretation of epigenomic patterns in colonic epithelia
(2015-12-18)
The methylation of cytosine nucleotides at the 5' position of DNA is a crucial epigenetic mechanism for the control of gene expression. Epigenome-wide associated studies have demonstrated that specific methylome patterns ...