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A refined model of nucleolar formation derived from the analysis of UBF variants and the hierarchical silencing of human nucleolar organizer regions
(NUI Galway, 2017-03-23)
The nucleolus, the largest sub-nuclear structure, forms around arrays of ribosomal RNA genes, termed nucleolar organizer regions (NORs). As the site of ribosome biogenesis, nucleolar function is intrinsically linked to ...