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Novel Multiplex Real-Time PCR Diagnostic Assay for Identification and Differentiation of Mycobacterium tuberculosis, Mycobacterium canettii, and Mycobacterium tuberculosis Complex Strains
(Journal of Clinical Microbiology, 2011-02)
Tuberculosis (TB) in humans is caused by members of the Mycobacterium tuberculosis complex (MTC). Rapid detection of the MTC is necessary for the timely initiation of antibiotic treatment, while differentiation between ...
Ecological variation in response to mass-flowering oilseed rape and surrounding landscape composition by members of a cryptic bumblebee complex
(Public Library of Science, 2013-06-19)
The Bombus sensu stricto species complex is a widespread group of cryptic bumblebee species which are important pollinators of many crops and wild plants. These cryptic species have, until now, largely been grouped together ...
Bumblebee learning and memory is impaired by chronic exposure to a neonicotinoid pesticide.
(Nature Publishing Group, 2015-11-16)
Bumblebees are exposed to pesticides applied for crop protection while foraging on treated plants, with increasing evidence suggesting that this sublethal exposure has implications for pollinator declines. The challenges ...
Manipulation of intestinal epithelial cell function by the cell contact-dependent type III secretion systems of Vibrio parahaemolyticus
(Frontiers Media, 2014-01-10)
Vibrio parahaemolyticus elicits gastroenteritis by deploying Type III Secretion Systems (TTSS) to deliver effector proteins into epithelial cells of the human intestinal tract. The bacteria must adhere to the human cells ...
Response of farmland biodiversity to the introduction of bioenergy crops: effects of local factors and surrounding landscape context
(Wiley Open Access, 2013-07-19)
The recent growth in bioenergy crop cultivation, stimulated by the need to implement measures to reduce net CO2 emissions, is driving major land-use changes with consequences for biodiversity and ecosystem service provision. ...
A Novel Multiplex Real-Time PCR for the Identification of Mycobacteria Associated with Zoonotic Tuberculosis
(PLoS ONE, 2011-08-09)
Background:
Tuberculosis (TB) is the leading cause of death worldwide from a single infectious agent. An ability to detect the Mycobacterium tuberculosis complex (MTC) in clinical material while simultaneously differentiating ...
Evolution and diversity of plant cell walls: from algae to flowering plants
(Annual Reviews, 2011-02-22)
All photosynthetic multicellular Eukaryotes, including land plants and algae, have cells that are surrounded by a dynamic, complex, carbohydrate-rich cell wall. The cell wall exerts considerable biological and biomechanical ...
Engineering recombinant antibodies for polymer biofunctionalization
(Wiley, 2015-08-18)
The attachment of recognition elements such as antibody fragments to polymeric substrates can be used to mediate cell- or protein-specific interactions. In this work, single-chain Fv (scFv) antibody fragments were isolated ...
Systems-based approaches to unravel multi-species microbial community functioning
(Research Network of Computational and Structural Biotechnology, 2014-12-03)
Some of the most transformative discoveries promising to enable the resolution of this century's grand societal
challenges will most likely arise from environmental science and particularly environmental microbiology ...
Comparative genome analysis identifies novel nucleic acid diagnostic targets for use in the specific detection of Haemophilus influenzae
(Elsevier, 2015-06-23)
Haemophilus influenzae is recognised as an important human pathogen associated with invasive infections, including bloodstream infection and meningitis. Currently used molecular-based diagnostic assays lack specificity in ...