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Novel Multiplex Real-Time PCR Diagnostic Assay for Identification and Differentiation of Mycobacterium tuberculosis, Mycobacterium canettii, and Mycobacterium tuberculosis Complex Strains
(Journal of Clinical Microbiology, 2011-02)
Tuberculosis (TB) in humans is caused by members of the Mycobacterium tuberculosis complex (MTC). Rapid detection of the MTC is necessary for the timely initiation of antibiotic treatment, while differentiation between ...
Ecological variation in response to mass-flowering oilseed rape and surrounding landscape composition by members of a cryptic bumblebee complex
(Public Library of Science, 2013-06-19)
The Bombus sensu stricto species complex is a widespread group of cryptic bumblebee species which are important pollinators of many crops and wild plants. These cryptic species have, until now, largely been grouped together ...
Manipulation of intestinal epithelial cell function by the cell contact-dependent type III secretion systems of Vibrio parahaemolyticus
(Frontiers Media, 2014-01-10)
Vibrio parahaemolyticus elicits gastroenteritis by deploying Type III Secretion Systems (TTSS) to deliver effector proteins into epithelial cells of the human intestinal tract. The bacteria must adhere to the human cells ...
Response of farmland biodiversity to the introduction of bioenergy crops: effects of local factors and surrounding landscape context
(Wiley Open Access, 2013-07-19)
The recent growth in bioenergy crop cultivation, stimulated by the need to implement measures to reduce net CO2 emissions, is driving major land-use changes with consequences for biodiversity and ecosystem service provision. ...
A Novel Multiplex Real-Time PCR for the Identification of Mycobacteria Associated with Zoonotic Tuberculosis
(PLoS ONE, 2011-08-09)
Background:
Tuberculosis (TB) is the leading cause of death worldwide from a single infectious agent. An ability to detect the Mycobacterium tuberculosis complex (MTC) in clinical material while simultaneously differentiating ...
Evolution and diversity of plant cell walls: from algae to flowering plants
(Annual Reviews, 2011-02-22)
All photosynthetic multicellular Eukaryotes, including land plants and algae, have cells that are surrounded by a dynamic, complex, carbohydrate-rich cell wall. The cell wall exerts considerable biological and biomechanical ...
Systems-based approaches to unravel multi-species microbial community functioning
(Research Network of Computational and Structural Biotechnology, 2014-12-03)
Some of the most transformative discoveries promising to enable the resolution of this century's grand societal
challenges will most likely arise from environmental science and particularly environmental microbiology ...
Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner
(Nature Publishing Group, 2014-05-01)
Nerve growth factor (NGF) is well characterised as an important pro-survival factor in neuronal cells that can inhibit apoptotic cell death upstream of mitochondrial outer membrane permeabilisation. Here we addressed the ...
Stress management at the ER: regulators of ER stress-induced apoptosis.
(Elsevier, 2012-02-17)
The endoplasmic reticulum (ER) is an elaborate cellular organelle essential for cell function and survival. Conditions that interfere with ER function lead to the accumulation and aggregation of unfolded proteins which are ...
Methods for Monitoring Endoplasmic Reticulum Stress and the Unfolded Protein Response
(2010)
The endoplasmic reticulum (ER) is the site of folding of membrane and secreted proteins in the cell. Physiological or pathological processes that disturb protein folding in the endoplasmic reticulum cause ER stress and ...