Browsing School of Natural Sciences by Title
Now showing items 110-129 of 166
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The nature of fracture permeability in the basement greywacke at Kawerau Geothermal Field, New Zealand
(Stanford University, 2012-01-30)The Mesozoic basement at Kawerau Geothermal Field comprises well indurated, inter-bedded sandstones and argillites with a complex structural history. These rocks have very low matrix porosity but nonetheless host both ... -
Nerve growth factor (NGF)-mediated regulation of p75(NTR) expression contributes to chemotherapeutic resistance in triple negative breast cancer cells
(Elsevier, 2016)Triple negative breast cancer [TNBC] cells are reported to secrete the neurotrophin nerve growth factor [NGF] and express its receptors, p75 neurotrophin receptor [p75(NTR)] and TrkA, leading to NGF-activated pro-survival ... -
Nerve Growth Factor in Cancer Cell Death and Survival
(MDPI, 2011-02)One of the major challenges for cancer therapeutics is the resistance of many tumor cells to induction of cell death due to pro-survival signaling in the cancer cells. Here we review the growing literature which shows that ... -
Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner
(Nature Publishing Group, 2014-05-01)Nerve growth factor (NGF) is well characterised as an important pro-survival factor in neuronal cells that can inhibit apoptotic cell death upstream of mitochondrial outer membrane permeabilisation. Here we addressed the ... -
Neuronal cell death in neurodegenerative diseases: recurring themes around protein handling
(Wiley, 2008-06-27)Neuronal cell death plays a role in many chronic neurodegenerative diseases with the loss of particular subsets of neurons. The loss of the neurons occurs during a period of many years, which can make the mode(s) of cell ... -
Neurotrophins and B-cell malignancies
(Springer Verlag, 2015-09-23)Neurotrophins and their receptors act as important proliferative and pro-survival factors in a variety of cell types. Neurotrophins are produced by multiple cell types in both pro and mature forms, and can act in an autocrine ... -
New Zealand geothermal power plants as critical facilities: an active fault avoidance study in the Wairakei Geothermal Field, New Zealand
(International Geothermal Association, 2015-04-19)Active faults in rifts commonly provide high crustal permeability and control geothermal fluid pathways. However, active faults can also pose surface deformation hazards to geothermal power plants and associated infrastructure. ... -
North Eastern Atlantic cephalopods stock assessment in a data limited framework Surplus Production in a Continuous Time (SPiCT): Annex1to WP.4.2deliverable
(Cephs and Chefs (Interreg Atlantic Area Community Engagement Publications), 2021)The lack of management leaves fishery resources vulnerable to increases in fishing pressure.Although some cephalopods are of commercial importance, most of Northeast Atlantic stocks are non-quota ... -
Novel Multiplex Real-Time PCR Diagnostic Assay for Identification and Differentiation of Mycobacterium tuberculosis, Mycobacterium canettii, and Mycobacterium tuberculosis Complex Strains
(Journal of Clinical Microbiology, 2011-02)Tuberculosis (TB) in humans is caused by members of the Mycobacterium tuberculosis complex (MTC). Rapid detection of the MTC is necessary for the timely initiation of antibiotic treatment, while differentiation between ... -
A Novel Multiplex Real-Time PCR for the Identification of Mycobacteria Associated with Zoonotic Tuberculosis
(PLoS ONE, 2011-08-09)Background: Tuberculosis (TB) is the leading cause of death worldwide from a single infectious agent. An ability to detect the Mycobacterium tuberculosis complex (MTC) in clinical material while simultaneously differentiating ... -
OpenTCC: An open source low-cost temperature-control chamber
(Elsevier, 2020-02-24)Microbial electrochemical technologies (MET) are emerging systems for environmental applications such as renewable energy production or pollution remediation. MET research often requires stable temperatures and low levels ... -
Opportunistic bacteria dominate the soil microbiome response to phenanthrene in a microcosm-based study
(Frontiers Media, 2018-11-21)Bioremediation offers a sustainable approach for removal of polycyclic aromatic hydrocarbons (PAHs) from the environment; however, information regarding the microbial communities involved remains limited. In this study, ... -
Optimizing fluorescent protein expression for quantitative fluorescence microscopy and spectroscopy using herpes simplex thymidine kinase promoter sequences
(Wiley, 2018-04-16)The modulation of expression levels of fluorescent fusion proteins (FFPs) is central for recombinant DNA technologies in modern biology as overexpression of proteins contributes to artifacts in biological experiments. In ... -
Organic waste biorefineries: Looking towards implementation
(Elsevier, 2020-07-16)The concept of biorefinery expands the possibilities to extract value from organic matter in form of either bespoke crops or organic waste. The viability of biorefinery schemes depends on the recovery of higher-value ... -
Partial reconstitution of DNA large loop repair with purified proteins from Saccharomyces cerevisiae
(OUP, 2008)Small looped mispairs are corrected by DNA mismatch repair. In addition, a distinct process called large loop repair (LLR) corrects heteroduplexes up to several hundred nucleotides in bacteria, yeast and human cells, and ... -
Pathogenic bacteria in our oceans' shellfish
(Microbiology Society, 2019-02)Mussels, oysters, clams – some of the most appetising culinary dishes, such as moules-frites, feature shellfish. These foods are considered healthy as they are fresh from the ocean, but looks can be deceiving. -
Pectin metabolism and assembly in the cell wall of the charophyte green alga penium margaritaceum
(American Society of Plant Biologists, 2014-03-20)The pectin polymer homogalacturonan (HG) is a major component of land plant cell walls and is especially abundant in the middle lamella. Current models suggest that HG is deposited into the wall as a highly methylesterified ... -
The performance of antimicrobial susceptibility testing programmes relevant to aquaculture and aquaculture products
(Food and Agriculture Organization of the United Nations (FAO), 2019)Antimicrobial susceptibility testing of bacteria isolated from aquatic animals and their environments may be performed either as part of a monitoring or surveillance programme or to provide guidance for clinical treatments ... -
Pollination ecology of Desmodium setigerum (Fabaceae) in Uganda; do big bees do it better?
(2016-09)Explosive pollen release is documented in many plant families, including the Fabaceae. Desmodium setigerum E. Mey (Fabaceae) is a perennial herb with single trip explosive pollen release found in eastern Africa, and the ... -
Population‐based identity‐by‐descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia
(Wiley, 2019-02-23)Genome‐wide association studies (GWASs) are highly effective at identifying common risk variants for schizophrenia. Rare risk variants are also important contributors to schizophrenia etiology but, with the exception of ...