Browsing School of Natural Sciences by Title
Now showing items 124-143 of 166
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Partial reconstitution of DNA large loop repair with purified proteins from Saccharomyces cerevisiae
(OUP, 2008)Small looped mispairs are corrected by DNA mismatch repair. In addition, a distinct process called large loop repair (LLR) corrects heteroduplexes up to several hundred nucleotides in bacteria, yeast and human cells, and ... -
Pathogenic bacteria in our oceans' shellfish
(Microbiology Society, 2019-02)Mussels, oysters, clams – some of the most appetising culinary dishes, such as moules-frites, feature shellfish. These foods are considered healthy as they are fresh from the ocean, but looks can be deceiving. -
Pectin metabolism and assembly in the cell wall of the charophyte green alga penium margaritaceum
(American Society of Plant Biologists, 2014-03-20)The pectin polymer homogalacturonan (HG) is a major component of land plant cell walls and is especially abundant in the middle lamella. Current models suggest that HG is deposited into the wall as a highly methylesterified ... -
The performance of antimicrobial susceptibility testing programmes relevant to aquaculture and aquaculture products
(Food and Agriculture Organization of the United Nations (FAO), 2019)Antimicrobial susceptibility testing of bacteria isolated from aquatic animals and their environments may be performed either as part of a monitoring or surveillance programme or to provide guidance for clinical treatments ... -
Pollination ecology of Desmodium setigerum (Fabaceae) in Uganda; do big bees do it better?
(2016-09)Explosive pollen release is documented in many plant families, including the Fabaceae. Desmodium setigerum E. Mey (Fabaceae) is a perennial herb with single trip explosive pollen release found in eastern Africa, and the ... -
Population‐based identity‐by‐descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia
(Wiley, 2019-02-23)Genome‐wide association studies (GWASs) are highly effective at identifying common risk variants for schizophrenia. Rare risk variants are also important contributors to schizophrenia etiology but, with the exception of ... -
Premitotic Assembly of Human CENPs -T and -W Switches Centromeric Chromatin to a Mitotic State.
(2011)Centromeres are differentiated chromatin domains, present once per chromosome, that direct segregation of the genome in mitosis and meiosis by specifying assembly of the kinetochore. They are distinct genetic loci in that ... -
Processing and analysis of high temperature geothermal acoustic borehole image logs in the Taupo Volcanic Zone, New Zealand
(Elsevier, 2014-06-19)Acoustic borehole televiewer (BHTV) logs provide direct observations of lithology, structure and in-situ stress in reservoirs, essential for successful well targeting and field management. Analyses of BHTV logs acquired ... -
Projected Range Contractions of European Protected Oceanic Montane Plant Communities: Focus on Climate Change Impacts Is Essential for Their Future Conservation
(PlosOne, 2014-04-21)Global climate is rapidly changing and while many studies have investigated the potential impacts of this on the distribution of montane plant species and communities, few have focused on those with oceanic montane affinities. ... -
Propionate production by bioelectrochemically-assisted lactate fermentation and simultaneous CO2 recycling
(Frontiers Media, 2020-12-15)Production of volatile fatty acids (VFAs), fundamental building blocks for the chemical industry, depends on fossil fuels but organic waste is an emerging alternative substrate. Lactate produced from sugar-containing waste ... -
The Proteasome Inhibitor Bortezomib Sensitizes AML with Myelomonocytic Differentiation to TRAIL Mediated Apoptosis
(2011)Acute myeloid leukemia (AML) is an aggressive stem cell malignancy that is difficult to treat. There are limitations to the current treatment regimes especially after disease relapse, and therefore new therapeutic agents ... -
Quantifying the stress distribution at the Rotokawa Geothermal Field, New Zealand
(New Zealand Geothermal Workshop, 2012)Knowledge of the orientation and magnitude of the principal stresses can be used to model the behavior of faults and fractures, and determine how they may influence fracture hosted permeability in geothermal reservoirs. ... -
Quantitative geometric description of fracture systems in an andesite lava flow using terrestrial laser scanner data
(Elsevier, 2017-06-03)Permeability hosted in andesitic lava flows is dominantly controlled by fracture systems, with geometries that are often poorly constrained. This paper explores the fracture system geometry of an andesitic lava flow formed ... -
Rapid and efficient cancer cell killing mediated by high-affinity death receptor homotrimerizing TRAIL variants
(Macmillan Publishers Limited, 2010)The tumour necrosis factor family member TNF-related apoptosis-inducing ligand (TRAIL) selectively induces apoptosis in a variety of cancer cells through the activation of death receptors 4 (DR4) and 5 (DR5) and is considered ... -
A rapid culture independent methodology to quantitatively detect and identify common human bacterial pathogens associated with contaminated high purity water
(BioMed Central, 2015-02-18)Water and High Purity Water (HPW) distribution systems can be contaminated with human pathogenic microorganisms. This biocontamination may pose a risk to human health as HPW is commonly used in the industrial, pharmaceutical ... -
Rapid screening for specific glycosylation and pathogen interactions on a 78 species avian egg white glycoprotein microarray
(Nature Research, 2017-07-25)There is an urgent need for discovery of novel antimicrobials and carbohydrate-based anti-adhesive strategies are desirable as they may not promote resistance. Discovery of novel anti-adhesive molecules from natural product ... -
Rapid unwinding of triplet repeat hairpins by Srs2 helicase of Saccharomyces cerevisiae
(2008)Expansions of trinucleotide repeats cause at least 15 heritable human diseases. Single-stranded triplet repeat DNA in vitro forms stable hairpins in a sequence-dependent manner that correlates with expansion risk in vivo. ... -
Reproducible, high-yielding, biological caproate production from food waste using a single-phase anaerobic reactor system
(BMC (part of Springer Nature), 2018-03-11)Background: Nowadays, the vast majority of chemicals are either synthesised from fossil fuels or are extracted from agricultural commodities. However, these production approaches are not environmentally and economically ... -
Response of farmland biodiversity to the introduction of bioenergy crops: effects of local factors and surrounding landscape context
(Wiley Open Access, 2013-07-19)The recent growth in bioenergy crop cultivation, stimulated by the need to implement measures to reduce net CO2 emissions, is driving major land-use changes with consequences for biodiversity and ecosystem service provision. ... -
Restriction of human polyomavirus BK virus DNA replication in murine cells and extracts
(2009)BK virus (BKV) causes persistent and asymptomatic infections in most humans and is the etiologic agent of polyomavirus-associated nephropathy (PVAN) and other pathologies. Unfortunately, there are no animal models with ...