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dc.contributor.authorSear, Richard P
dc.contributor.authorPagonabarraga, Ignacio
dc.contributor.authorFlaus, Andrew
dc.date.accessioned2018-09-20T16:24:14Z
dc.date.available2018-09-20T16:24:14Z
dc.date.issued2015-02-25
dc.identifier.citationSear, Richard P; Pagonabarraga, Ignacio; Flaus, Andrew (2015). Life at the mesoscale: the self-organised cytoplasm and nucleoplasm. BMC Biophysics 8 ,
dc.identifier.issn2046-1682
dc.identifier.urihttp://hdl.handle.net/10379/13845
dc.description.abstractThe cell contains highly dynamic structures exploiting physical principles of self-organisation at the mesoscale (100 nm to 10 mu m). Examples include non-membrane bound cytoplasmic bodies, cytoskeleton-based motor networks and multi-scale chromatin organisation. The challenges of mesoscale self-organisation were discussed at a CECAM workshop in July 2014. Biologists need approaches to observe highly dynamic, low affinity, low specificity associations and to perturb single structures, while biological physicists and biomathematicians need to work closely with biologists to build and validate quantitative models. A table of terminology is included to facilitate multidisciplinary efforts to reveal the richness and diversity of mesoscale cell biology.
dc.publisherSpringer Nature
dc.relation.ispartofBMC Biophysics
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Ireland
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/3.0/ie/
dc.subjectworkshop report
dc.subjectself-organisation
dc.subjectmesoscale
dc.subjectcell biology
dc.subjectcytoskeleton
dc.subjectcytoplasmic bodies
dc.subjectchromatin
dc.subjectgranules
dc.subjectmotors
dc.titleLife at the mesoscale: the self-organised cytoplasm and nucleoplasm
dc.typeArticle
dc.identifier.doi10.1186/s13628-015-0018-6
dc.local.publishedsourcehttps://bmcbiophys.biomedcentral.com/track/pdf/10.1186/s13628-015-0018-6?site=bmcbiophys.biomedcentral.com
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Attribution-NonCommercial-NoDerivs 3.0 Ireland
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