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Now showing items 461-470 of 559
A kinetic modelling study of alcohols operating regimes in a HCCI engine
(SAE International, 2017-09-04)
Pursuing a sustainable energy scenario for transportation requires the blending of renewable oxygenated fuels such as alcohols into commercial hydrocarbon fuels. From a chemical kinetic perspective, this requires the ...
Cost-effective wireless microcontroller for internet connectivity of open-source chemical devices
(American Chemical Society, 2018-06-04)
This paper presents a system for remote monitoring of turbidity data that can detect light intensity and temperature using a microcontroller and the Internet of Things. The system comprises a light dependent resistor and ...
A phosphate-targeted dinuclear Cu(II) complex combining major groove binding and oxidative DNA cleavage
(Oxford University Press, 2018-09-17)
Free radical generation is an inevitable consequence of aerobic existence and is implicated in a wide variety of pathological conditions including cancer, cardiovascular disease, ageing and neurodegenerative disorder. Free ...
Cocrystal forms of the BCS class IV drug sulfamethoxazole
(American Chemical Society, 2018-05-23)
Sulfamethoxazole, smz, is an antibiotic that is classified as a Biopharmaceutics Classification System (BCS) class IV, low solubility and low permeability drug. Cocrystal formation has been examined in an attempt to improve ...
Teaming up synthetic chemistry and histochemistry for activity screening in galectin-directed inhibitor design
(Springer, 2016-06-24)
A hallmark of endogenous lectins is their ability to select a few distinct glycoconjugates as counterreceptors for functional pairing from the natural abundance of cellular glycoproteins and glycolipids. As a consequence, ...
Ligand design for somatostatin receptor isoforms 4 and 5
(Elsevier, 2018-11-17)
The somatostatin receptor (SSTR) isoforms, SSTR-4 and SSTR-5 are targets in numerous disorders and diseases. Although there has been some success in achieving selective isoform inhibition, structure-based drug design and ...
Interpretive review of the acoustic borehole image logs acquired to date in the Wairakei-Tauhara Geothermal Field
(Institute of Geological and Nuclear Sciences Limited, 2013)
[No abstract available]
The in vivo potential-regulated protective protein of nitrogenase in azotobacter vinelandii supports aerobic bioelectrochemical dinitrogen reduction in vitro
(American Chemical Society, 2017-06-08)
Nitrogenase, the only enzyme known to be able to reduce dinitrogen (N-2) to ammonia (NH3), is irreversibly damaged upon exposure to molecular oxygen (O-2). Several microbes, however, are able to grow aerobically and ...
Application of ball milling for highly selective mechanochemical polymorph transformations
(American Chemical Society, 2018-06-07)
Milling is an important secondary processing technique in the manufacture of pharmaceuticals, primarily used as a particle size reduction process. p-Aminobenzoic acid (PABA), m-aminobenzoic acid (MABA), o-aminobenzoic acid ...
Electro-mechanical response of a 3D nerve bundle model to mechanical loads leading to axonal injury
(Wiley, 2017-11-21)
Traumatic brain injuries and damage are major causes of death and disability. We propose a 3D fully coupled electro-mechanical model of a nerve bundle to investigate the electrophysiological impairments due to trauma at ...