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Now showing items 161-169 of 169
Mrc1, Tof1 and Csm3 inhibit CAG·CTG repeat instability by at least two mechanisms
(Springer, 2008)
Trinucleotide repeats frequently expand and contract in humans and model organisms. Protein factors that modulate this process have been found by candidate gene approaches or mutant screens for increased expansion ...
Bcl-2 family on guard at the ER
(American Physiological Society, 2009)
The endoplasmic reticulum (ER) is the main site for protein folding, lipid biosynthesis and calcium storage in the cell. Disturbances of these critical cellular functions lead to
ER stress. The ER responds to disturbances ...
Evidence for long-term Gamma-ray and X-ray variability from the unidentified TeV source HESS J0632+057
(2009)
HESS J0632+057 is one of only two unidentified very-high-energy gamma-ray sources which appear to be point-like within experimental resolution. It is possibly associated with the massive Be star MWC 148 and has been suggested ...
Optical pulsations from the anomalous X-ray pulsar 1E 1048.1-5937
(2009)
We present high-speed optical photometry of the anomalous X-ray pulsar 1E 1048.1-5937 obtained with ULTRACAM on the 8.2-m Very Large Telescope in June 2007. We detect 1E 1048.1-5937 at a magnitude of i'=25.3+/-0.2, consistent ...
Expansions of CAG·CTG repeats in immortalized human astrocytes.
(Oxford University Press, 2007)
Expansions of trinucleotide repeats (TNRs) are the genetic cause for a number of neurodegenerative disorders. In some of these diseases, ongoing somatic expansions in the brain are thought to contribute to disease progression. ...
Rapid unwinding of triplet repeat hairpins by Srs2 helicase of Saccharomyces cerevisiae
(2008)
Expansions of trinucleotide repeats cause at least 15 heritable human diseases. Single-stranded triplet repeat DNA in vitro forms stable hairpins in a sequence-dependent manner that correlates with expansion risk in vivo. ...
The cell walls of pteridophytes and other green plants - a review
(British Pteridological Society, 2006-12-22)
The cell wall is one of the defining characteristics of plants and is a fundamental
component in normal growth and development. Cell wall composition is a
potentially valuable source of phylogenetic information as notable ...
Effect of substrate geometry on liquid-crystal-mediated nanocylinder-substrate interactions
(American Institute of Physics, 2008)
Using classical density functional theory, the liquid crystal (LC)-mediated interaction between a cylindrical nanoparticle and a structured substrate is studied. The surface is structured by cutting a rectangular groove ...
Quantitative analysis of cocaine in solid mixtures using Raman spectroscopy and chemometric methods
(Wiley, 2000-04-27)
Near-infrared (785 mn) excitation was used to obtain Raman spectra from a series of 33 solid mixtures containing cocaine, caffeine and glucose (9.8-80.6% by weight cocaine), which were then analysed using chemometric ...