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Partial reconstitution of DNA large loop repair with purified proteins from Saccharomyces cerevisiae
Small looped mispairs are corrected by DNA mismatch repair. In addition, a distinct process called large loop repair (LLR) corrects heteroduplexes up to several hundred nucleotides in bacteria, yeast and human cells, and ...
Mrc1, Tof1 and Csm3 inhibit CAG·CTG repeat instability by at least two mechanisms
Trinucleotide repeats frequently expand and contract in humans and model organisms. Protein factors that modulate this process have been found by candidate gene approaches or mutant screens for increased expansion ...