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1064 nm acoustic resolution photoacoustic microscopy
(Wiley, 2018-12-03)
Photoacoustic imaging is a noninvasive imaging technique having the advantages of high-optical contrast and good acoustic resolution at improved imaging depths. Light transport in biological tissues is mainly characterized ...
Label free ultra-sensitive imaging with sub-diffraction spatial resolution
(IEEE, 2019-07-09)
In this paper, we show a new way to break the resolution limit and dramatically improve sensitivity to structural
changes. To realize it we developed a novel label free contrast mechanism, based on the spectral encoding ...
Spatial frequency domain correlation mapping optical coherence tomography for nanoscale structural characterization
(AIP Publishing, 2019-09-16)
Most of the fundamental pathological processes in living tissues exhibit changes at the nanoscale. Noninvasive, label-free detection of structural changes in biological samples pose a significant challenge to both researchers ...
Noninvasive detection of nanoscale structural changes in cornea associated with cross-linking treatment
(Wiley, 2020-02-17)
Corneal cross-linking (CXL) using ultraviolet-A (UVA) irradiation with a riboflavin photosensitizer has grown from an interesting concept to a practical clinical treatment for corneal ectatic diseases globally, such as ...
Characterization of nanosensitive multifractality in submicron scale tissue morphology and its alteration in tumor progression
(Society of Photo-optical Instrumentation Engineers, 2021-01-11)
Significance: Assessment of disease using optical coherence tomography is an actively investigated problem, owing to many unresolved challenges in early disease detection, diagnosis, and treatment response monitoring. The ...
Nanoscale structure detection and monitoring of tumour growth with optical coherence tomography
(Royal Society of Chemistry, 2020-05-25)
Approximately 90% of cancers originate in epithelial tissues leading to epithelial thickening, but the ultrastructural changes and underlying architecture are less well known. Depth resolved label free visualization of ...