Browsing College of Science by Author "Zhou, Yi"
Now showing items 1-6 of 6
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Accessing depth-resolved high spatial frequency content from the optical coherence tomography signal
Alexandrov, Sergey; Arangath, Anand; Zhou, Yi; Murphy, Mary; Duffy, Niamh; Neuhaus, Kai; Shaw, Georgina; McAuley, Ryan; Leahy, Martin (Nature Research, 2021-08-24)Optical coherence tomography (OCT) is a rapidly evolving technology with a broad range of applications, including biomedical imaging and diagnosis. Conventional intensity-based OCT provides depth-resolved imaging with a ... -
Nanoscale structure detection and monitoring of tumour growth with optical coherence tomography
Das, Nandan; Sergey, Alexandrov; Zhou, Yi; Gilligan, Katie E.; Dwyer, Róisín M.; Leahy, Martin (Royal Society of Chemistry, 2020-05-25)Approximately 90% of cancers originate in epithelial tissues leading to epithelial thickening, but the ultrastructural changes and underlying architecture are less well known. Depth resolved label free visualization of ... -
Nanosensitive optical coherence tomography to assess wound healing within the cornea
Lal, Cerine; Alexandrov, Sergey; Rani, Sweta; Zhou, Yi; Ritter, Thomas; Leahy, Martin (Optical Society of America, 2020-05-01)Optical coherence tomography (OCT) is a non-invasive depth resolved optical imaging modality, that enables high resolution, cross-sectional imaging in biological tissues and materials at clinically relevant depths. Though ... -
Noninvasive detection of nanoscale structural changes in cornea associated with cross-linking treatment
Zhou, Yi; Alexandrov, Sergey; Nolan, Andrew; Das, Nandan; Dey, Rajib; Leahy, Martin (Wiley, 2020-02-17)Corneal cross-linking (CXL) using ultraviolet-A (UVA) irradiation with a riboflavin photosensitizer has grown from an interesting concept to a practical clinical treatment for corneal ectatic diseases globally, such as ... -
Simple characterization scheme for optical coherence tomography systems with application to a commercial and a near-isometric resolution fibre-based system
Dey, Rajib; Zhou, Yi; Neuhaus, Kai; Alexandrov, Sergey; Nolan, Andrew; Chang, Ting-Chiao; Leahy, Martin (2021-12-14)Optical Coherence Tomography (OCT) is a rapidly growing imaging modality in biomedical optics. OCT can perform high-resolution, cross-sectional imaging of the microstructure of biological tissues by measuring the coherent ... -
Spatial frequency domain correlation mapping optical coherence tomography for nanoscale structural characterization
Alexandrov, Sergey; McNamara, Paul M.; Das, Nandan; Zhou, Yi; Lynch, Gillian; Hogan, Josh; Leahy, Martin (AIP Publishing, 2019-09-16)Most of the fundamental pathological processes in living tissues exhibit changes at the nanoscale. Noninvasive, label-free detection of structural changes in biological samples pose a significant challenge to both researchers ...