Browsing College of Science by Author "Pallipurath, Anuradha R."
Now showing items 1-4 of 4
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A comprehensive cocrystal screening study of chlorothiazide
Aljohani, Marwah; Pallipurath, Anuradha R.; McArdle, Patrick; Erxleben, Andrea (American Chemical Society, 2017-09-01)Cocrystal formation of chlorothiazide (ctz) was screened with a variety of coformers with carboxyl, amide, hydroxyl, sulfonamide, pyridine, amidine, and amine functional groups. New cocrystals with acetamide (aca), benzamide ... -
A comprehensive spectroscopic study of the polymorphs of diflunisal and their phase transformations
Pallipurath, Anuradha R.; Civati, Francesco; Sibik, Juraj; Crowley, Clare; Zeitler, J. Axel; McArdle, Patrick; Erxleben, Andrea (Elsevier, 2017-06-08)Understanding phase transitions in pharmaceutical materials is of vital importance for drug manufacturing, processing and storage. In this paper we have carried out comprehensive high-resolution spectroscopic studies on ... -
Sulfamerazine: Understanding the influence of slip planes in the polymorphic phase transformation through X-ray crystallographic studies and ab initio lattice dynamics
Pallipurath, Anuradha R.; Skelton, Jonathan M.; Warren, Mark R.; Kamali, Naghmeh; McArdle, Patrick; Erxleben, Andrea (American Chemical Society, 2015-08-28)Understanding the polymorphism exhibited by organic active-pharmaceutical ingredients (APIs), in particular the relationships between crystal structure and the thermodynamics of polymorph stability, is vital for the ... -
Tailoring cocrystal and salt formation and controlling the crystal habit of diflunisal
Pallipurath, Anuradha R.; Civati, Francesco; Eziashi, Magdalene; Omar, Elaf; McArdle, Patrick; Erxleben, Andrea (American Chemical Society, 2016-09-26)Crystal habit modification of the drug diflunisal that normally grows into extremely thin, long needles has been achieved by breaking the stacking effect with the help of coformers. Eight new cocrystals are reported, along ...