Show simple item record

Defective neutrophil rolling and transmigration in acute uremia

dc.contributor.authorPindjakova, Jana
dc.contributor.authorGriffin, Matthew D.
dc.date.accessioned2018-09-20T16:21:40Z
dc.date.available2018-09-20T16:21:40Z
dc.date.issued2011-09-01
dc.identifier.citationPindjakova, Jana; Griffin, Matthew D. (2011). Defective neutrophil rolling and transmigration in acute uremia. Kidney International 80 (5), 447-450
dc.identifier.issn0085-2538
dc.identifier.urihttp://hdl.handle.net/10379/13482
dc.description.abstractCirculating neutrophils are essential for innate immunity and undergo rapid, stepwise adhesion to and transmigration through the endothelium following tissue injury and microbial invasion. Neutrophil dysfunction may contribute to morbidity and mortality in acute kidney injury but has not frequently been studied at a mechanistic level. Rossaint et al. provide experimental evidence in mice and humans that acute uremia causes discrete intracellular signaling abnormalities that interfere with specific stages of neutrophil trafficking during inflammation. Kidney International (2011) 80, 447-450. doi:10.1038/ki.2011.169
dc.publisherElsevier BV
dc.relation.ispartofKidney International
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Ireland
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/3.0/ie/
dc.subjectlung injury
dc.subjectinflammation
dc.subjectnephrectomy
dc.subjectinfection
dc.subjectadhesion
dc.subjectfailure
dc.titleDefective neutrophil rolling and transmigration in acute uremia
dc.typeArticle
dc.identifier.doi10.1038/ki.2011.169
dc.local.publishedsourcehttps://doi.org/10.1038/ki.2011.169
nui.item.downloads0


Files in this item

Thumbnail
Name:
license.txt
Size:
5.659Kb
Format:
Text file
View/Open

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivs 3.0 Ireland
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Ireland