Show simple item record

dc.contributor.authorMcGrath, Emer R
dc.contributor.authorEspie, Colin A
dc.contributor.authorMurphy, Andrew W
dc.contributor.authorNewell, John
dc.contributor.authorPower, Alice
dc.contributor.authorMadden, Sarah
dc.contributor.authorByrne, Molly
dc.contributor.authorO’Donnell, Martin J
dc.date.accessioned2018-09-20T16:17:08Z
dc.date.available2018-09-20T16:17:08Z
dc.date.issued2014-10-09
dc.identifier.citationMcGrath, Emer R; Espie, Colin A; Murphy, Andrew W; Newell, John; Power, Alice; Madden, Sarah; Byrne, Molly; O’Donnell, Martin J (2014). Sleep to lower elevated blood pressure: study protocol for a randomized controlled trial. Trials 15 ,
dc.identifier.issn1745-6215
dc.identifier.urihttp://hdl.handle.net/10379/12793
dc.description.abstractBackground: Sleep is an essential component of good physical and mental health. Previous studies have reported that poor quality sleep is associated with an increased risk of hypertension and cardiovascular disease. Hypertension is the most common and important risk factor for cardiovascular disease, and even modest reductions in blood pressure can result in significant reductions in the risk of stroke and myocardial infarction. In this trial, we will determine the efficacy of an online sleep intervention in improving blood pressure, in participants with hypertension and poor sleep quality. Methods: Trial design: Randomized-controlled, two-group, parallel, blinded, single-center, Phase II trial of 134 participants. Population and recruitment: Primary prevention population of participants with hypertension (systolic blood pressure, 130 to 160 mm Hg; diastolic blood pressure, < 110 mm Hg) and poor sleep quality in a community setting. Intervention: Multicomponent online sleep intervention consisting of sleep information, sleep hygiene education, and cognitive behavioral therapy. Comparator: Standardized cardiovascular risk factor and lifestyle-education session (usual care). Primary outcome: Change in mean 24-hour ambulatory systolic blood pressure between baseline and 8-week follow-up. Hypertension has been selected as the primary outcome measure because of its robust association with both poor sleep quality and cardiovascular disease. Statistical analyses: Intention-to-treat analysis by using a linear mixed model.
dc.publisherSpringer Nature
dc.relation.ispartofTrials
dc.subjectsleep
dc.subjecthypertension
dc.subjectcardiovascular disease
dc.subjectcognitive-behavioral therapy
dc.subjectclinical effectiveness trial
dc.subjectrisk-factor
dc.subjectcardiovascular-disease
dc.subjectpersistent insomnia
dc.subjectinsufficient sleep
dc.subjectduration
dc.subjecthypertension
dc.subjectmetaanalysis
dc.subjectassociation
dc.titleSleep to lower elevated blood pressure: study protocol for a randomized controlled trial
dc.typeArticle
dc.identifier.doi10.1186/1745-6215-15-393
dc.local.publishedsourcehttps://trialsjournal.biomedcentral.com/track/pdf/10.1186/1745-6215-15-393
nui.item.downloads0


Files in this item

This item appears in the following Collection(s)

Show simple item record