dc.contributor.author | McAnena, P. | |
dc.contributor.author | Lowery, A. | |
dc.contributor.author | Kerin, M. J. | |
dc.date.accessioned | 2018-09-20T16:16:28Z | |
dc.date.available | 2018-09-20T16:16:28Z | |
dc.date.issued | 2018-01-01 | |
dc.identifier.citation | McAnena, P. Lowery, A.; Kerin, M. J. (2018). Role of micro-rnas in breast cancer surgery. British Journal of Surgery 105 (2), E19-E30 | |
dc.identifier.issn | 0007-1323 | |
dc.identifier.uri | http://hdl.handle.net/10379/12703 | |
dc.description.abstract | Background: The management of breast cancer has changed dramatically in the molecular era. Micro-RNAs can contribute to multiple facets of cancer surgery.
Methods: This narrative review, based on years of research on the role of micro-RNAs, focused on the potential of these small, robust RNAs to influence all aspects of breast cancer surgery.
Results: Micro-RNAs have a potential role as biomarkers in the diagnosis, prognosis and evaluation of response to therapy in breast cancer. They may also contribute to future therapeutic strategies.
Conclusion: The molecular era has changed understanding of cancer. Micro-RNAs have the potential for use in personalized cancer strategies. | |
dc.publisher | Wiley-Blackwell | |
dc.relation.ispartof | British Journal of Surgery | |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Ireland | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/3.0/ie/ | |
dc.subject | brca2 mutation carriers | |
dc.subject | lymph-node metastasis | |
dc.subject | circulating micrornas | |
dc.subject | tumor-suppressor | |
dc.subject | receptor status | |
dc.subject | nuclear export | |
dc.subject | up-regulation | |
dc.subject | early-stage | |
dc.subject | expression | |
dc.subject | cells | |
dc.title | Role of micro-rnas in breast cancer surgery | |
dc.type | Article | |
dc.identifier.doi | 10.1002/bjs.10790 | |
dc.local.publishedsource | http://onlinelibrary.wiley.com/doi/10.1002/bjs.10790/pdf | |
nui.item.downloads | 0 | |