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dc.contributor.authorMcAnena, P.
dc.contributor.authorLowery, A.
dc.contributor.authorKerin, M. J.
dc.date.accessioned2018-09-20T16:16:28Z
dc.date.available2018-09-20T16:16:28Z
dc.date.issued2018-01-01
dc.identifier.citationMcAnena, P. Lowery, A.; Kerin, M. J. (2018). Role of micro-rnas in breast cancer surgery. British Journal of Surgery 105 (2), E19-E30
dc.identifier.issn0007-1323
dc.identifier.urihttp://hdl.handle.net/10379/12703
dc.description.abstractBackground: The management of breast cancer has changed dramatically in the molecular era. Micro-RNAs can contribute to multiple facets of cancer surgery. Methods: This narrative review, based on years of research on the role of micro-RNAs, focused on the potential of these small, robust RNAs to influence all aspects of breast cancer surgery. Results: Micro-RNAs have a potential role as biomarkers in the diagnosis, prognosis and evaluation of response to therapy in breast cancer. They may also contribute to future therapeutic strategies. Conclusion: The molecular era has changed understanding of cancer. Micro-RNAs have the potential for use in personalized cancer strategies.
dc.publisherWiley-Blackwell
dc.relation.ispartofBritish Journal of Surgery
dc.subjectbrca2 mutation carriers
dc.subjectlymph-node metastasis
dc.subjectcirculating micrornas
dc.subjecttumor-suppressor
dc.subjectreceptor status
dc.subjectnuclear export
dc.subjectup-regulation
dc.subjectearly-stage
dc.subjectexpression
dc.subjectcells
dc.titleRole of micro-rnas in breast cancer surgery
dc.typeArticle
dc.identifier.doi10.1002/bjs.10790
dc.local.publishedsourcehttp://onlinelibrary.wiley.com/doi/10.1002/bjs.10790/pdf
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