Show simple item record

dc.contributor.authorMackle, Joseph N.
dc.contributor.authorBlond, David J.-P.
dc.contributor.authorMooney, Emma
dc.contributor.authorMcDonnell, Caitlin
dc.contributor.authorBlau, Werner J.
dc.contributor.authorShaw, Georgina
dc.contributor.authorBarry, Frank P.
dc.contributor.authorMurphy, J. Mary
dc.contributor.authorBarron, Valerie
dc.date.accessioned2018-09-20T16:15:18Z
dc.date.available2018-09-20T16:15:18Z
dc.date.issued2011-07-04
dc.identifier.citationMackle, Joseph N. Blond, David J.-P.; Mooney, Emma; McDonnell, Caitlin; Blau, Werner J.; Shaw, Georgina; Barry, Frank P.; Murphy, J. Mary; Barron, Valerie (2011). In vitro characterization of an electroactive carbon-nanotube-based nanofiber scaffold for tissue engineering. Macromolecular Bioscience 11 (9), 1272-1282
dc.identifier.issn1616-5187
dc.identifier.urihttp://hdl.handle.net/10379/12553
dc.description.abstractIn an effort to reduce organ replacement and enhance tissue repair, there has been a tremendous effort to create biomechanically optimized scaffolds for tissue engineering applications. In contrast, the development and characterization of electroactive scaffolds has attracted little attention. Consequently, the creation and characterization of a carbon nanotube based poly(lactic acid) nanofiber scaffold is described herein. After 28 d in physiological solution at 37 degrees C, a change in the mass, chemical properties and polymer morphology is seen, while the mechanical properties and physical integrity are unaltered. No adverse cytotoxic affects are seen when mesenchymal stem cells are cultured in the presence of the scaffold. Taken together, these data auger well for electroactive tissue engineering.
dc.publisherWiley-Blackwell
dc.relation.ispartofMacromolecular Bioscience
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Ireland
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/3.0/ie/
dc.subjectcarbon nanotubes
dc.subjectdegradation profile
dc.subjectelectroactive scaffolds
dc.subjectmesenchymal stem cell response
dc.subjectpoly(lactic acid)
dc.subjectmesenchymal stem-cells
dc.subjectmechanical-properties
dc.subjectpolymer
dc.subjectnanocomposites
dc.subjectproliferation
dc.subjectdegradation
dc.subjectpolyaniline
dc.subjectcomposites
dc.titleIn vitro characterization of an electroactive carbon-nanotube-based nanofiber scaffold for tissue engineering
dc.typeArticle
dc.identifier.doi10.1002/mabi.201100029
dc.local.publishedsourcehttp://researchrepository.ucd.ie/bitstream/10197/5011/2/Paper125.pdf
nui.item.downloads0


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivs 3.0 Ireland
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Ireland