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dc.contributor.authorLi, Dandan
dc.contributor.authorFu, You-Jun
dc.contributor.authorRusling, James F.
dc.date.accessioned2018-09-20T16:14:29Z
dc.date.available2018-09-20T16:14:29Z
dc.date.issued2015-01-01
dc.identifier.citationLi, Dandan; Fu, You-Jun; Rusling, James F. (2015). Characterizing protein modifications by reactive metabolites using magnetic bead bioreactors and lc-ms/ms. Chem. Commun. 51 (22), 4701-4703
dc.identifier.issn1359-7345,1364-548X
dc.identifier.urihttp://hdl.handle.net/10379/12441
dc.description.abstractWe report here label-free metabolite-protein adduct detection and identification employing magnetic beads coated with metabolic enzymes as bioreactors to generate metabolites and possible metabolite-protein adducts for analysis by liquid chromatographytandem mass spectrometry.
dc.publisherRoyal Society of Chemistry (RSC)
dc.relation.ispartofChem. Commun.
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Ireland
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/3.0/ie/
dc.subjectglutathione-s-transferase
dc.subjectinduced hepatic-necrosis
dc.subjectmass-spectrometry
dc.subjectcovalent binding
dc.subjecttoxicity
dc.subjectacetaminophen
dc.subjectmechanisms
dc.subjectdrug
dc.subjectelectrophiles
dc.subjectparacetamol
dc.titleCharacterizing protein modifications by reactive metabolites using magnetic bead bioreactors and lc-ms/ms
dc.typeArticle
dc.identifier.doi10.1039/c5cc00420a
dc.local.publishedsourcehttp://europepmc.org/articles/pmc4348200?pdf=render
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Attribution-NonCommercial-NoDerivs 3.0 Ireland
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Ireland