dc.contributor.author | Kgosidialwa, Oratile | |
dc.contributor.author | Egan, Aoife M. | |
dc.contributor.author | Carmody, Louise | |
dc.contributor.author | Kirwan, Breda | |
dc.contributor.author | Gunning, Patricia | |
dc.contributor.author | Dunne, Fidelma P. | |
dc.date.accessioned | 2018-09-20T16:13:06Z | |
dc.date.available | 2018-09-20T16:13:06Z | |
dc.date.issued | 2015-12-01 | |
dc.identifier.citation | Kgosidialwa, Oratile; Egan, Aoife M. Carmody, Louise; Kirwan, Breda; Gunning, Patricia; Dunne, Fidelma P. (2015). Treatment with diet and exercise for women with gestational diabetes mellitus diagnosed using iadpsg criteria. The Journal of Clinical Endocrinology & Metabolism 100 (12), 4629-4636 | |
dc.identifier.issn | 0021-972X,1945-7197 | |
dc.identifier.uri | http://hdl.handle.net/10379/12247 | |
dc.description.abstract | Context: Prevalence of gestational diabetes mellitus (GDM) and obesity continue to increase.
Objective: This study aimed to ascertain whether diet and exercise is a successful intervention for women with GDM and whether a subset of these women have comparable outcomes to those with normal glucose tolerance (NGT).
Design, Setting, and Participants: This was a retrospective cohort study of five antenatal centers along the Irish Atlantic seaboard of 567 women diagnosed with GDM and 2499 women with NGT during pregnancy.
Intervention: Diet and exercise therapy on diagnosis of GDM were prescribed and multiple maternal and neonatal outcomes were examined.
Results: Infants of women with GDM were more likely to be hypoglycemic (adjusted odds ratio [aOR], 7.25; 95% confidence interval [CI], 2.94-17.9) at birth. They were more likely to be admitted to the neonatal intensive care unit (aOR, 2.16; 95% CI, 1.60-2.91). Macrosomia and large-forgestational-age rates were lower in the GDM group (aOR, 0.48; 95% CI, 0.37-0.64 and aOR, 0.61; 95% CI, 0.46-0.82, respectively). There was no increase in small for gestational age among offspring of women with GDM (aOR, 0.81; 95% CI, 0.49-1.34). Women with diet-treated GDM and body mass index (BMI) <25 kg/m(2) had similar outcomes to those with NGT of the same BMI group. Obesity increased risk for poor pregnancy outcomes regardless of diabetes status.
Conclusion: Medical nutritional therapy and exercise for women with GDM may be successful in lowering rates of large for gestational age and macrosomia without increasing small-for-gestational- age rates. Women with GDM and a BMI less than 25kg/m(2) had outcomes similar to those with NGT suggesting that these women could potentially be treated in a less resource intensive setting. | |
dc.publisher | The Endocrine Society | |
dc.relation.ispartof | The Journal of Clinical Endocrinology & Metabolism | |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Ireland | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/3.0/ie/ | |
dc.subject | body-mass index | |
dc.subject | glucose-tolerant women | |
dc.subject | pregnancy study-groups | |
dc.subject | atlantic-dip | |
dc.subject | weight-gain | |
dc.subject | international association | |
dc.subject | glycemic control | |
dc.subject | outcomes | |
dc.subject | hyperglycemia | |
dc.subject | obesity | |
dc.title | Treatment with diet and exercise for women with gestational diabetes mellitus diagnosed using iadpsg criteria | |
dc.type | Article | |
dc.identifier.doi | 10.1210/jc.2015-3259 | |
dc.local.publishedsource | https://academic.oup.com/jcem/article-pdf/100/12/4629/10423499/jcem4629.pdf | |
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