Now showing items 1-3 of 3
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
(Nature Publishing Group (Macmillan), 2013-03-27)
Breast cancer is the most common cancer among women. Common variants at 27 loci have been identified as associated with susceptibility to breast cancer, and these account for ~9% of the familial risk of the disease. We ...
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.
(Nature Publishing Group (Macmillan), 2013-04)
TERT-locus SNPs and leukocyte telomere measures are reportedly associated with risks of multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed ~480 SNPs at the TERT locus in breast (n = 103,991), ...
11q13 is a susceptibility locus for hormone receptor positive breast cancer.
A recent two-stage genome-wide association study (GWAS) identified five novel breast cancer susceptibility loci on chromosomes 9, 10, and 11. To provide more reliable estimates of the relative risk associated with these ...