Now showing items 1-6 of 6
Preparing New Doctors for Clinical Practice: An Evaluation of Pre-Internship Training
A consistent finding in the literature is that newly graduated medical students often do not possess the basic skills required to perform their job. Training designed to prepare newly graduated medical students for internship ...
Relationship between circulating and tissue microRNAs in a murine model of breast cancer.
MiRNAs are key regulators of tumorigenesis that are aberrantly expressed in the circulation and tissue of patients with cancer. The aim of this study was to determine whether miRNA dysregulation in the circulation reflected ...
MicroRNA expression in colorectal cancer.
(IOS Press, 2012-12-17)
Colorectal cancer is a common disease entity with a multi-factorial aetiology which remains poorly understood. It is estimated that in 2008, colorectal cancerwas responsible for 8% of all cancer deaths, making it the fourth ...
11q13 is a susceptibility locus for hormone receptor positive breast cancer.
A recent two-stage genome-wide association study (GWAS) identified five novel breast cancer susceptibility loci on chromosomes 9, 10, and 11. To provide more reliable estimates of the relative risk associated with these ...
The KRAS-Variant Is Associated with Risk of Developing Double Primary Breast and Ovarian Cancer
Purpose: A germline microRNA binding site-disrupting variant, the KRAS-variant (rs61764370), is associated with an increased risk of developing several cancers. Because this variant is most strongly associated with ovarian ...
Mesenchymal stem cells in the colorectal tumor microenvironment: Recent progress and implications
Mesenchymal stem cells (MSCs) are nonhematopoietic multipotent adult stem cells. They have been shown to have a natural tropism for many tumors types, including colorectal, and are capable of escaping host immune surveillance. ...