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Now showing items 31-40 of 58
Performance Monitoring of a Mammalian Cell Based Bioprocess using Raman spectroscopy.
(2013)
Being able to predict the final product yield at all stages in long-running, industrial, mammalian cell culture processes is vital for both operational efficiency, process consistency, and the implementation of Quality by ...
Monitoring cell culture media degradation using surface enhanced Raman scattering (SERS) spectroscopy
(Elsevier (Science Direct), 2014-06-13)
The quality of the cell culture media used in biopharmaceutical manufacturing is a crucial factor affecting bioprocess performance and the quality of the final product. Due to their complex composition these media are ...
Comparison of the fluorescence behavior of a biocrude oil and crude petroleum oils
(ACS Publications (American Chemical Society), 2006-02-15)
The production and characterization of biocrude and petroleum like products from natural, renewable resources such as oil-bearing plant seeds is an interesting area of research at the moment. The present article discusses ...
Comprehensive, quantitative bioprocess productivity monitoring using fluorescence EEM spectroscopy and chemometrics
(Royal Society of Chemistry, 2014)
This study demonstrates the application of fluorescence excitation-emission matrix (EEM) spectroscopy to the quantitative predictive analysis of recombinant glycoprotein production cultured in a Chinese hamster ovary (CHO) ...
Frequency domain fluorescence lifetime study of crude petroleum oils
(Springer Verlag, 2008-02-01)
Frequency domain (FD) fluorescence lifetime data was collected for a series of 20 crude petroleum oils using a 405 nm excitation source and over a spectral range of similar to 426 to similar to 650 nm. Average fluorescence ...
An excitation emission fluorescence lifetime spectrometer using a frequency doubled supercontinuum laser source
(IOP Publishing, 2018-09-03)
The accurate fluorescence analysis of complex, multi-fluorophore containing proteins requires the use of multi-dimensional measurement techniques. For the measurement of intrinsic fluorescence from tyrosine (Tyr) and ...
A fluorescence anisotropy method for measuring protein concentration in complex cell culture media
(Elsevier, 2014-03-12)
The rapid, quantitative analysis of the complex cell culture media used in biopharmaceutical manufacturing is of critical importance. Requirements for cell culture media composition profiling, or changes in specific analyte ...
A F-bridged Mn(II) molecular square
(RSC, 2009-10-08)
We report on a tetranuclear Mn(II) complex possessing a F-bridged molecular square topology directed by 1,10-phenanthroline ligands.
Extended wavelength anisotropy resolved multidimensional emission spectroscopy (ARMES) measurements: better filters, validation standards, and Rayleigh scatter removal methods
(IOP Publishing, 2017-08-17)
Anisotropy resolved multidimensional emission spectroscopy (ARMES) provides valuable insights into multi-fluorophore proteins (Groza et al 2015 Anal. Chim. Acta 886 133-42). Fluorescence anisotropy adds to the multidimensional ...
Cell culture media analysis using rapid spectroscopic methods
(Elsevier, 2018-09-24)
Cell culture media (CCM) used in industrial biotechnology are complex mixtures of molecules and elements that are inherently difficult to analyze comprehensively. CCM quality analysis is of utmost importance for efficient ...