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Prediction of Cell Culture Media Performance Using Fluorescence Spectroscopy
(2010)
Cell culture media used in industrial mammalian cell culture are complex aqueous solutions that are inherently difficult to analyze comprehensively. The analysis of media quality and variance is of utmost importance in ...
Applications of raman spectroscopy in biopharmaceutical manufacturing: A short review
(Sage Publications, 2017-05-23)
The production of active pharmaceutical ingredients (APIs) is currently undergoing its biggest transformation in a century.
The changes are based on the rapid and dramatic introduction of protein- and macromolecule-based ...
Rapid quantification of tryptophan and tyrosine in chemically defined cell culture media using fluorescence spectroscopy
(2012)
The rapid and inexpensive analysis of the complex cell culture media used in industrial mammalian cell culture is required for quality and variance monitoring. Excitation-emission matrix (EEM) spectroscopy combined with ...
Using surface-enhanced Raman scattering (SERS) and fluorescence spectroscopy for screening yeast extracts, a complex component of cell culture media
(2012)
Yeastolate or yeast extract, which are hydrolysates produced by autolysis of yeast, are often employed as a raw material in the media used for industrial mammalian cell culture. The source and quality of yeastolate can ...
Low-content quantification in powders using Raman spectroscopy: a facile chemometric approach to sub 0.1% limits of detection.
(American Chemical Society, 2015-02-23)
A robust and accurate analytical methodology for low-content (<0.1%) quantification in the
solid-state using Raman spectroscopy, sub-sampling, and chemometrics was demonstrated using
a piracetam–proline model. The method ...
Rapid characterization and quality control of complex cell culture media solutions using Raman spectroscopy and chemometrics
(2010)
The use of Raman spectroscopy coupled with chemometrics for the rapid identification, characterization, and quality assessment of Complex cell culture media components used for industrial mammalian cell culture was ...
Fluorescence EEM Spectroscopy for Rapid Identification and Quality Evaluation of Cell Culture Media Components.
(Ingenta, 2011-11)
The application of fluorescence excitation-emission matrix (EEM) spectroscopy to the quantitative analysis of complex, aqueous solutions of cell culture media components was investigated. These components, yeastolate, ...
Prediction of Cell Culture Media performance using Fluorescence Spectroscopy
(ACS Publications, 2010)
Cell culture media used in industrial mammalian cell culture are complex aqueous solutions that are inherently difficult to analyze comprehensively. The analysis of media quality and variance is of utmost importance in ...
Prediction of cell culture media performance using fluorescence spectroscopy.
(American Chemical Society, 2010)
Cell culture media used in industrial mammalian cell culture are complex aqueous solutions that are inherently difficult to analyze comprehensively. The analysis of media quality and variance is of utmost importance in ...
Performance Monitoring of a Mammalian Cell Based Bioprocess using Raman spectroscopy.
(2013)
Being able to predict the final product yield at all stages in long-running, industrial, mammalian cell culture processes is vital for both operational efficiency, process consistency, and the implementation of Quality by ...