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Prediction of Cell Culture Media Performance Using Fluorescence Spectroscopy
(2010)
Cell culture media used in industrial mammalian cell culture are complex aqueous solutions that are inherently difficult to analyze comprehensively. The analysis of media quality and variance is of utmost importance in ...
Applications of raman spectroscopy in biopharmaceutical manufacturing: A short review
(Sage Publications, 2017-05-23)
The production of active pharmaceutical ingredients (APIs) is currently undergoing its biggest transformation in a century.
The changes are based on the rapid and dramatic introduction of protein- and macromolecule-based ...
Classification of narcotics in solid mixtures using principal component analysis and Raman spectroscopy
(ASTM International, 2002-03-01)
Eighty-five solid samples consisting of illegal narcotics diluted with several different materials were analyzed by near-infrared (785 nm excitation) Raman spectroscopy. Principal Component Analysis (PCA) was employed to ...
Rapid quantification of tryptophan and tyrosine in chemically defined cell culture media using fluorescence spectroscopy
(2012)
The rapid and inexpensive analysis of the complex cell culture media used in industrial mammalian cell culture is required for quality and variance monitoring. Excitation-emission matrix (EEM) spectroscopy combined with ...
Using surface-enhanced Raman scattering (SERS) and fluorescence spectroscopy for screening yeast extracts, a complex component of cell culture media
(2012)
Yeastolate or yeast extract, which are hydrolysates produced by autolysis of yeast, are often employed as a raw material in the media used for industrial mammalian cell culture. The source and quality of yeastolate can ...
Low-content quantification in powders using Raman spectroscopy: a facile chemometric approach to sub 0.1% limits of detection.
(American Chemical Society, 2015-02-23)
A robust and accurate analytical methodology for low-content (<0.1%) quantification in the
solid-state using Raman spectroscopy, sub-sampling, and chemometrics was demonstrated using
a piracetam–proline model. The method ...
Quantitative analysis of cocaine in solid mixtures using Raman spectroscopy and chemometric methods
(Wiley, 2000)
Near-infrared (785 mn) excitation was used to obtain Raman spectra from a series of 33 solid mixtures containing cocaine, caffeine and glucose (9.8-80.6% by weight cocaine), which were then analysed using chemometric ...
Identifications and quantitative measurements of narcotics in solid mixtures using near-IR Raman spectroscopy and multivariate analysis
(1999)
Raman spectroscopy offers the potential for the identification of illegal narcotics in seconds by inelastic scattering of light from molecular vibrations. In this study cocaine, heroin, and MDMA were analyzed using near-IR ...
Rapid characterization and quality control of complex cell culture media solutions using Raman spectroscopy and chemometrics
(2010)
The use of Raman spectroscopy coupled with chemometrics for the rapid identification, characterization, and quality assessment of Complex cell culture media components used for industrial mammalian cell culture was ...
Fluorescence EEM Spectroscopy for Rapid Identification and Quality Evaluation of Cell Culture Media Components.
(Ingenta, 2011-11)
The application of fluorescence excitation-emission matrix (EEM) spectroscopy to the quantitative analysis of complex, aqueous solutions of cell culture media components was investigated. These components, yeastolate, ...