Browsing School of Chemistry by Subject "Cell culture media"
Now showing items 1-7 of 7
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Anisotropy resolved multidimensional emission spectroscopy (ARMES): A new tool for protein analysis
(Elsevier, 2015-07-30)Structural analysis of proteins using the emission of intrinsic fluorophores is complicated by spectral overlap. Anisotropy resolved multidimensional emission spectroscopy (ARMES) overcame the overlap problem by the use ... -
Applications of raman spectroscopy in biopharmaceutical manufacturing: A short review
(Sage Publications, 2017-05-23)The production of active pharmaceutical ingredients (APIs) is currently undergoing its biggest transformation in a century. The changes are based on the rapid and dramatic introduction of protein- and macromolecule-based ... -
Comprehensive, quantitative bioprocess productivity monitoring using fluorescence EEM spectroscopy and chemometrics
(Royal Society of Chemistry, 2014)This study demonstrates the application of fluorescence excitation-emission matrix (EEM) spectroscopy to the quantitative predictive analysis of recombinant glycoprotein production cultured in a Chinese hamster ovary (CHO) ... -
Monitoring cell culture media degradation using surface enhanced Raman scattering (SERS) spectroscopy
(Elsevier (Science Direct), 2014-06-13)The quality of the cell culture media used in biopharmaceutical manufacturing is a crucial factor affecting bioprocess performance and the quality of the final product. Due to their complex composition these media are ... -
Prediction of cell culture media performance using fluorescence spectroscopy.
(American Chemical Society, 2010)Cell culture media used in industrial mammalian cell culture are complex aqueous solutions that are inherently difficult to analyze comprehensively. The analysis of media quality and variance is of utmost importance in ... -
A rapid fluorescence based method for the quantitative analysis of cell culture media photo-degradation
(Elsevier (Science Direct), 2013-11-21)Cell culture media are very complex chemical mixtures that are one of the most important aspects in biopharmaceutical manufacturing. The complex composition of many media leads to materials that are inherently unstable and ... -
Rapid quantification of tryptophan and tyrosine in chemically defined cell culture media using fluorescence spectroscopy
(2012)The rapid and inexpensive analysis of the complex cell culture media used in industrial mammalian cell culture is required for quality and variance monitoring. Excitation-emission matrix (EEM) spectroscopy combined with ...